CAS 508-71-4|(10β)-10,18-Epoxyros-15-ene-7,18-dione

Introduction:Basic information about CAS 508-71-4|(10β)-10,18-Epoxyros-15-ene-7,18-dione, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(10β)-10,18-Epoxyros-15-ene-7,18-dione
CAS Number508-71-4Molecular Weight316.43
Density1.1±0.1 g/cm3Boiling Point449.0±45.0 °C at 760 mmHg
Molecular FormulaC20H28O3Melting Point/
MSDS/Flash Point196.2±28.8 °C

Names

Namerosenonolactone
SynonymMore Synonyms

(10β)-10,18-Epoxyros-15-ene-7,18-dione BiologicalActivity

DescriptionRosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin and cholesterol ester transfer protein[1][2][3].
Related CatalogSignaling Pathways >>Metabolic Enzyme/Protease >>ThrombinResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>CETP
References

[1]. Anis I, et al. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo). 2002;50(4):515-518  

[2]. Anis I, Ahmed S, Malik A, Yasin A, Choudary MI. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo). 2002;50(4):515-518.  

[3]. Wang Y, Zhang L, Wang F, Li ZH, Dong ZJ, Liu JK. New Diterpenes from Cultures of the Fungus Engleromyces goetzii and Their CETP Inhibitory Activity [published online ahead of print, 2015 Apr 8]. Nat Prod Bioprospect. 2015;5(2):69-75.  

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point449.0±45.0 °C at 760 mmHg
Molecular FormulaC20H28O3
Molecular Weight316.43
Flash Point196.2±28.8 °C
Exact Mass316.203857
PSA43.37000
LogP3.63
Vapour Pressure0.0±1.1 mmHg at 25°C
Index of Refraction1.541
InChIKeyHWECMADGHQKSLK-KZGWPWDHSA-N
SMILESC=CC1(C)CCC2(C)C(C1)C(=O)CC1C3(C)CCCC12OC3=O

Safety Information

Hazard CodesXi

Synonyms

9H-4a,1-(Epoxymethano)phenanthrene-9,12-dione, 7-ethenyldodecahydro-1,4b,7-trimethyl-, (1S,4aR,4bR,7R,8aR,10aS)-
9H-4a,1-(Epoxymethano)phenanthrene-9,12-dione, 7-ethenyldodecahydro-1,4b,7-trimethyl-, (1R,4aR,4bR,7R,8aR,10aS)-
(10β)-10,18-Epoxyros-15-ene-7,18-dione
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