Introduction：Basic information about CAS 52190-55-3|m-PEG4-SH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG4-SH |
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| CAS Number | 52190-55-3 | Molecular Weight | 224.31800 |
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| Density | 1.035 | Boiling Point | / |
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| Molecular Formula | C9H20O4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol |
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| Synonym | More Synonyms |
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m-PEG4-SH BiologicalActivity
| Description | m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.035 |
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| Molecular Formula | C9H20O4S |
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| Molecular Weight | 224.31800 |
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| Exact Mass | 224.10800 |
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| PSA | 75.72000 |
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| LogP | 0.61240 |
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| InChIKey | VXEBAWYHFQRROQ-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCS |
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| Storage condition | 2-8°C |
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Synonyms
| 3,6,9,12-Tetraoxatridecane-1-thiol |
| 2,5,8,11-TETRAOXATRIDECANE-13-THIOL |
