Introduction：Basic information about CAS 76296-72-5|Polyphyllin II, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Polyphyllin II |
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| CAS Number | 76296-72-5 | Molecular Weight | 871.016 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C44H70O16 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Polyphyllin B |
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| Synonym | More Synonyms |
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Polyphyllin II BiologicalActivity
| Description | Polyphyllin II is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
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| References | [1]. Wang W, et al. Apoptosis in HepaRG and HL-7702 cells inducted by polyphyllin II through caspases activation and cell-cycle arrest. J Cell Physiol. 2019 May;234(5):7078-7089. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C44H70O16 |
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| Molecular Weight | 871.016 |
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| Exact Mass | 870.461304 |
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| PSA | 255.91000 |
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| LogP | 6.02 |
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| Index of Refraction | 1.628 |
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| InChIKey | AWKXNOOUWFJCMU-WMRBLUSKSA-N |
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| SMILES | CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(OC7OC(CO)C(O)C7O)C(OC7OC(C)C(O)C(O)C7O)C6O)CCC5(C)C4CCC3(C)C1C2C |
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Safety Information
| Safety Phrases | 24/25 |
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| HS Code | 29389090 |
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Synonyms
| β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl O-α-L-arabinofuranosyl-(1->4)-O-[6-deoxy-α-L-mannopyranosyl-(1->3)]- |
| (3β,25R)-17-Hydroxyspirost-5-en-3-yl α-L-arabinofuranosyl-(1->4)-[6-deoxy-α-L-mannopyranosyl-(1->3)]-β-D-glucopyranoside |
| PolyphyllinD |
| N1953 |
| Polyphyllin II |
