CAS 3788-44-1|H-TYR-HIS-OH

Introduction:Basic information about CAS 3788-44-1|H-TYR-HIS-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameH-TYR-HIS-OH
CAS Number3788-44-1Molecular Weight318.32800
Density/Boiling Point/
Molecular FormulaC15H18N4O4Melting Point/
MSDS/Flash Point/

Names

Name(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
SynonymMore Synonyms

H-TYR-HIS-OH BiologicalActivity

DescriptionTyrosylhistidine is a dipeptide consisting of tyrosine and histidine (Tyr-His). Tyrosylhistidine is an orally active antihypertensive peptide. Tyrosylhistidine reduces blood pressure in mice in a model of spontaneous hypertension[1].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others
References

[1]. Suetsuna K, et al. Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. J Nutr Biochem. 2004 May;15(5):267-72.  

Chemical & Physical Properties

Molecular FormulaC15H18N4O4
Molecular Weight318.32800
Exact Mass318.13300
PSA141.33000
LogP0.88840
InChIKeyZQOOYCZQENFIMC-STQMWFEESA-N
SMILESNC(Cc1ccc(O)cc1)C(=O)NC(Cc1cnc[nH]1)C(=O)O

Synonyms

L-Tyr-L-His
L-Histidine,N-L-tyrosyl
tyrosylhistidine
L-tyrosyl-L-histidine
L-Histidine,L-tyrosyl
H-Tyr-His-OH
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