Introduction：Basic information about CAS 27219-07-4|Boc-NH-C4-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Boc-NH-C4-acid |
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| CAS Number | 27219-07-4 | Molecular Weight | 217.262 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 331.7±27.0 °C at 760 mmHg |
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| Molecular Formula | C10H19NO4 | Melting Point | 48-52 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 154.4±23.7 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid |
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| Synonym | More Synonyms |
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Boc-NH-C4-acid BiologicalActivity
| Description | Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl/ether |
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| References | [1]. [1].Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 331.7±27.0 °C at 760 mmHg |
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| Melting Point | 48-52 °C(lit.) |
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| Molecular Formula | C10H19NO4 |
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| Molecular Weight | 217.262 |
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| Flash Point | 154.4±23.7 °C |
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| Exact Mass | 217.131409 |
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| PSA | 75.63000 |
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| LogP | 0.84 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.475 |
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| InChIKey | GFMRZAMDGJIWRB-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCCCC(=O)O |
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| Storage condition | 2-8°C |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 5-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)pentanoic acid |
| 5-[(tert-Butoxycarbonyl)amino]pentanoic acid |
| 5-(N-t-butoxycarbonylamino)pentanoic acid |
| 5-[[(1,1-Dimethylethoxy)carbonyl]amino]-pentanoic acid |
| MFCD00076903 |
| 5-[(tert-Butoxycarbonyl)amino]valeric Acid |
| 5-(Boc-amino)valeric acid |
| Boc-5-Ava-OH |
| N-(tert-Butoxycarbonyl)-5-aminovaleric Acid |
| 2-Methyl-2-propanyl 6-hydroxy-6-oxonorleucinate |
| Hexanedioic acid, 2-amino-, 1-(1,1-dimethylethyl) ester |
| 5-(Boc-amino)pentanoic Acid |
| 5-(tert-Butoxycarbonylamino)pentanoic Acid |
| 5-(N-Boc-amino)valeric acid |
| N-Boc-5-aminovaleric Acid |
| 5-Boc-amino-pentanoic acid |
| 5-(tert-Butoxycarbonylamino)valeric Acid |
| N-Boc-5-aminopentanoic Acid |
| 5-(N-t-butoxycarbonylamino)valeric acid |
| Pentanoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]- |
| boc-5-aminovaleric acid |
| 5-(N-tert-butoxycarbonylamino)-pentanoic acid |
| 5-(N-t-butyloxycarbonylamino)-pentanoic acid |
| N-(tert-Butoxycarbonyl)-5-aminopentanoic Acid |
| Boc-5-aminopentanoic acid |
