Introduction：Basic information about CAS 6991-10-2|Swertisin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Swertisin |
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| CAS Number | 6991-10-2 | Molecular Weight | 462.404 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 798.1±60.0 °C at 760 mmHg |
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| Molecular Formula | C22H22O11 | Melting Point | / |
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| MSDS | / | Flash Point | 279.7±26.4 °C |
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Names
| Name | apigenin 6-glucosyl-7-o-methyl ether |
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| Synonym | More Synonyms |
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Swertisin BiologicalActivity
| Description | Swertisin, a C-glucosylflavone isolated from Swertia japonica, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist[1][2]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic DiseaseSignaling Pathways >>GPCR/G Protein >>Adenosine Receptor |
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| References | [1]. Oh HK, et al. Swertisin ameliorates pre-pulse inhibition deficits and cognitive impairment induced by MK-801 in mice. J Psychopharmacol. 2017 Feb;31(2):250-259. [2]. Lee HE, et al. Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property. Behav Brain Res. 2016 Jun 1;306:137-45. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 798.1±60.0 °C at 760 mmHg |
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| Molecular Formula | C22H22O11 |
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| Molecular Weight | 462.404 |
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| Flash Point | 279.7±26.4 °C |
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| Exact Mass | 462.116211 |
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| PSA | 179.28000 |
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| LogP | -1.03 |
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| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
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| Index of Refraction | 1.695 |
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| InChIKey | ABRULANJVVJLFI-DGHBBABESA-N |
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| SMILES | COc1cc2oc(-c3ccc(O)cc3)cc(=O)c2c(O)c1C1OC(CO)C(O)C(O)C1O |
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Synonyms
| SWERTISIN |
| SWERTISIN(P) |
| 4H-1-Benzopyran-4-one, 6-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy- |
| Sorbifolin 6-O-β-glucopyranoside |
| apigenin-7-methylether-6-C-glucoside |
| 6-C-glucopyranosyl-7-O-methylapigenin |
| 7-O-methylapigenin mono-6-C-glucoside |
| 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4-oxo-4H-chromen-6-yl β-D-glucopyranoside |
