Introduction:Basic information about CAS 2362-62-1|4-Methylbenzenecarbothioamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
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Determination of p-methylthiobenzamide and p-methylthiobenzamide-S-oxide from rat plasma using solid-phase extraction and high-performance liquid chromatography.
J. Chromatogr. A. 567(1) , 213-20, (1991)
p-Methylthiobenzamide (PMTB) is a thiocarbonyl compound exhibiting marked hepatotoxicity and nephrotoxicity. We describe a high-performance liquid chromatographic method for analyzing PMTB and a metab...
The effect of partial hepatectomy on the metabolism, distribution, and nephrotoxicity of para-methylthiobenzamide in the rat.
Toxicol. Appl. Pharmacol. 113(2) , 246-52, (1992)
Para-Methylthiobenzamide (PMTB) produces injury to the liver and kidney. Toxicity is mediated via its biotransformation to a reactive S,S-dioxide metabolite. The objective of this study was to examine...