Introduction：Basic information about CAS 52386-42-2|Emofolin sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Emofolin sodium |
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| CAS Number | 52386-42-2 | Molecular Weight | 473.48200 |
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| Density | 1.58g/cm3 | Boiling Point | / |
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| Molecular Formula | C21H27N7O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | L-Glutamic acid, N-[4-[[2-(2-amino-1,4,5,6,7,8-hexahydro- 5-methyl-4-oxo-6-pteridinyl)ethyl]amino]benzoyl]-, disodium salt |
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Emofolin sodium BiologicalActivity
| Description | Ketotrexate sodium is an orally active antifolate and immunosuppressant. Ketotrexate sodium has good anti-inflammatory activity and is widely used in rheumatoid arthritis (RA). Ketotrexate sodium is used in research into cancer and autoimmune diseases[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>AntifolateResearch Areas >>Inflammation/Immunology |
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| References | [1]. Puig L. Methotrexate: new therapeutic approaches. Actas Dermosifiliogr. 2014 Jul-Aug;105(6):583-9. [2]. Torres RP, et al. Methotrexate: Implications of pharmacogenetics in the treatment of patients with Rheumatoid Arthritis. ARP Rheumatol. 2022 Oct 1;1(3):225-229. |
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Chemical & Physical Properties
| Density | 1.58g/cm3 |
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| Molecular Formula | C21H27N7O6 |
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| Molecular Weight | 473.48200 |
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| Exact Mass | 473.20200 |
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| PSA | 203.03000 |
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| LogP | 1.79280 |
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| InChIKey | PASPSZYIMAFFFK-HNYZGNTBSA-L |
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| SMILES | CN1c2c(nc(N)[nH]c2=O)NCC1CCNc1ccc(C(=O)NC(CCC(=O)[O-])C(=O)[O-])cc1.[Na+].[Na+] |
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