CAS 74805-91-7|Methylophiopogonanone B

Introduction：Basic information about CAS 74805-91-7|Methylophiopogonanone B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Methylophiopogonanone B BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Methylophiopogonanone B
CAS Number	74805-91-7	Molecular Weight	328.359
Density	1.285	Boiling Point	554.5±49.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₀O₅	Melting Point	/
MSDS	/	Flash Point	201.5±23.3 °C

Names

Name	(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one
Synonym	More Synonyms

Methylophiopogonanone B BiologicalActivity

Description	Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Ras
References	[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root. [2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

Description

Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Ras

References

[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.

[2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

Chemical & Physical Properties

Density	1.285
Boiling Point	554.5±49.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₀O₅
Molecular Weight	328.359
Flash Point	201.5±23.3 °C
Exact Mass	328.131073
PSA	75.99000
LogP	5.22
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.617
InChIKey	UFMAZRUMVFVHLY-CYBMUJFWSA-N
SMILES	COc1ccc(CC2COc3c(C)c(O)c(C)c(O)c3C2=O)cc1

Safety Information

Hazard Codes	Xi

Synonyms

methylophiopogonanone B

Methyl o-nitrophenylacetate

4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-, (3R)-

2-nitrophenylacetic acid methyl ester

(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one

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