CAS 81686-22-8|Sodium ionophore III
Introduction：Basic information about CAS 81686-22-8|Sodium ionophore III, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sodium ionophore III | ||
|---|---|---|---|
| CAS Number | 81686-22-8 | Molecular Weight | 552.78800 |
| Density | 1.12g/cm3 | Boiling Point | 709.4ºC at 760 mmHg |
| Molecular Formula | C34H52N2O4 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 382.8ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | N,N-dicyclohexyl-2-[2-[2-(dicyclohexylamino)-2-oxoethoxy]phenoxy]acetamide |
|---|---|
| Synonym | More Synonyms |
Sodium ionophore III BiologicalActivity
| Description | Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc. |
|---|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Sodium ChannelResearch Areas >>Cardiovascular Disease |
| In Vitro | Preincubation of the cells with the Na+ ionophore sodium ionophore III not only stimulated caffeate reduction, but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeate reduction immediately dissipated the intracellular ATP level[1]. Lactate-sulfate grown cells are insensitive to the Na+ ionophore, ETH2120[2]. Sodium ionophore III ligand is a very effective receptor for the Eu3+ and Am3+ cations and can be considered as a potential extraction agent for nuclear iste treatment[3]. |
| References | [1]. Imkamp F, et al. Chemiosmotic energy conservation with Na(+) as the coupling ion during hydrogen-dependent caffeate reduction by Acetobacterium woodii. J Bacteriol. 2002 Apr;184(7):1947-51. [2]. Wang L, et al. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis. PeerJ. 2016 Apr 14;4:e1919. [3]. Makrlík, E, et al. Sodium Ionophore III as Very Effective Receptor for Trivalent Europium and Americium.J Solution Chem (2016) 45: 463. |
Chemical & Physical Properties
| Density | 1.12g/cm3 |
|---|---|
| Boiling Point | 709.4ºC at 760 mmHg |
| Molecular Formula | C34H52N2O4 |
| Molecular Weight | 552.78800 |
| Flash Point | 382.8ºC |
| Exact Mass | 552.39300 |
| PSA | 59.08000 |
| LogP | 7.43220 |
| Index of Refraction | 1.564 |
| InChIKey | GKRBLFCTFPAHMH-UHFFFAOYSA-N |
| SMILES | O=C(COc1ccccc1OCC(=O)N(C1CCCCC1)C1CCCCC1)N(C1CCCCC1)C1CCCCC1 |
| Storage condition | 2-8℃ |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H335 |
| Precautionary Statements | P261 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 37 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles1
More Articles| T. Maruizumi et al. Mikrochim. Acta I , 331, (1986) |
Synonyms
| N,N,N',N'-Tetracyclohexyl-1,2-phenylenedioxydiacetamide |
| N,N-Dicyclohexyl-2-(2-[2-(dicyclohexylamino)-2-oxoethoxy]phenoxy)acetamide |
| ETH 2120 |
| MFCD00077941 |
| Sodium ionophore III |
| Acetamide,2,2'-[1,2-phenylenebis(oxy)]bis[N,N-dicyclohexyl |
