CAS 24579-14-4|4-HYDROXYWARFARIN

Introduction：Basic information about CAS 24579-14-4|4-HYDROXYWARFARIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Safety Information
4. Customs
5. Articles5
6. Synonyms

Common Name	4-HYDROXYWARFARIN
CAS Number	24579-14-4	Molecular Weight	324.32700
Density	1.384g/cm3	Boiling Point	522ºC at 760mmHg
Molecular Formula	C₁₉H₁₆O₅	Melting Point	/
MSDS	ChineseUSA	Flash Point	190.3ºC
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	4-hydroxy-3-[1-(4-hydroxyphenyl)-3-oxobutyl]chromen-2-one
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.384g/cm3
Boiling Point	522ºC at 760mmHg
Molecular Formula	C₁₉H₁₆O₅
Molecular Weight	324.32700
Flash Point	190.3ºC
Exact Mass	324.10000
PSA	87.74000
LogP	3.31520
Vapour Pressure	1E-11mmHg at 25°C
Index of Refraction	1.658
InChIKey	RRZWAMPDGRWRPF-UHFFFAOYSA-N
SMILES	CC(=O)CC(c1ccc(O)cc1)c1c(O)c2ccccc2oc1=O

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H318
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22-41
Safety Phrases	26-39
RIDADR	NONH for all modes of transport
HS Code	2914501900

Customs

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles5

Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.

Chem. Res. Toxicol. 23(5) , 939-45, (2010)

Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how meta...

Metabolism of R- and S-warfarin by CYP2C19 into four hydroxywarfarins.

Drug Metab. Lett. 6(3) , 157-64, (2012)

Coumadin (R/S-warfarin) is a highly efficacious and widely used anticoagulant; however, its highly variable metabolism remains an important contributor to uncertainties in therapeutic responses. Pharm...

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

Drug Metab. Lett. 4(4) , 213-9, (2010)

Effective coumadin (R/S-warfarin) therapy is complicated by inter-individual variability in metabolism. Recent studies have demonstrated that CYP3A isoforms likely contribute to patient responses and ...

Synonyms

4-Hydroxywarfarin

4'-Hydroxywarfarin

Recommended......