Introduction：Basic information about CAS 76060-35-0|1-Dehydro-6-gingerdione, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1-Dehydro-6-gingerdione |
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| CAS Number | 76060-35-0 | Molecular Weight | 290.35400 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 448.9±40.0 °C at 760 mmHg |
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| Molecular Formula | C17H22O4 | Melting Point | / |
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| MSDS | / | Flash Point | 159.3±20.8 °C |
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Names
| Name | 1-(4-hydroxy-3-methoxyphenyl)dec-1-ene-3,5-dione |
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| Synonym | More Synonyms |
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1-Dehydro-6-gingerdione BiologicalActivity
| Description | 6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
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| In Vitro | 6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1]. 6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1]. 6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1]. Apoptosis Analysis[1] Cell Line: Hep G2 cells. Concentration: 0, 50, 100 μM. Incubation Time: 24 h. Result: Induced Apoptosis in Hep G2 Cells. |
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| References | [1]. Chung-Yi Chen, et al. 6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. J Agric Food Chem. 2010 May 12;58(9):5604-11. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 448.9±40.0 °C at 760 mmHg |
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| Molecular Formula | C17H22O4 |
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| Molecular Weight | 290.35400 |
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| Flash Point | 159.3±20.8 °C |
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| Exact Mass | 290.15200 |
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| PSA | 63.60000 |
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| LogP | 3.52260 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.546 |
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| InChIKey | JUKHKHMSQCQHEN-VQHVLOKHSA-N |
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| SMILES | CCCCCC(=O)CC(=O)C=Cc1ccc(O)c(OC)c1 |
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Synonyms
| 1-Decene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)- |
| 1-(4-Hydroxy-3-methoxyphenyl)-1-decene-3,5-dione |
| [6]-Dehydrogingerdione |
| 1-Dehydro-6-gingerdione |
