CAS 22255-13-6|Guaijaverin
| Common Name | Guaijaverin | ||
|---|---|---|---|
| CAS Number | 22255-13-6 | Molecular Weight | 434.350 |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 828.1±65.0 °C at 760 mmHg |
| Molecular Formula | C20H18O11 | Melting Point | / |
| MSDS | USA | Flash Point | 296.3±27.8 °C |
Names
| Name | Guaijaverin |
|---|---|
| Synonym | More Synonyms |
Guaijaverin BiologicalActivity
| Description | Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| Target | IC50: 120 μM (Urease)[1] |
| In Vitro | Guaijaverin has anti-Strep.mutans activity, with MIC values of 4 and 2 mg/ml for MTCC 1943 and CLSM 001 strain of Strep. mutans, respectively[3]. |
| References | [1]. Shabana S, et al. Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava. Biosci Biotechnol Biochem. 2010;74(4):878-80. [2]. Caruso IP, et al. Exploring the binding mechanism of Guaijaverin to human serum albumin: fluorescencespectroscopy and computational approach. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov;97:449-55. [3]. Prabu GR, et al. Guaijaverin -- a plant flavonoid as potential antiplaque agent against Streptococcus mutans. J Appl Microbiol. 2006 Aug;101(2):487-95. |
Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 828.1±65.0 °C at 760 mmHg |
| Molecular Formula | C20H18O11 |
| Molecular Weight | 434.350 |
| Flash Point | 296.3±27.8 °C |
| Exact Mass | 434.084900 |
| PSA | 190.28000 |
| LogP | 1.68 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.802 |
| InChIKey | PZZRDJXEMZMZFD-IEGSVRCHSA-N |
| SMILES | O=c1c(OC2OCC(O)C(O)C2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 |
| Storage condition | room temp |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
Articles7
More Articles| Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava. Biosci. Biotechnol. Biochem. 74 , 878-880, (2010) Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease in... | |
| Guaijaverin -- a plant flavonoid as potential antiplaque agent against Streptococcus mutans. J. Appl. Microbiol. 101 , 487-495, (2006) The aim of the present study was to investigate the anti-Streptococcus mutans activity and the in vitro effects of subminimal inhibitory concentrations of guaijaverin isolated from Psidium guajava Lin... | |
| Benzophenones and flavonoids from Hypericum maculatum and their antioxidant activities. Nat. Prod. Res. 26 , 1576-1583, (2012) The occurrence of three known benzophenones, namely annulatophenonoside, acetylannulatophenonoside and annulatophenone as well as a flavonol O-glycoside guajaverin in the aerial parts of Hypericum mac... |
Synonyms
| 3-(α-L-Arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
| Quercetin-3-Arabinoside |
| 4H-1-Benzopyran-4-one, 3-(α-L-arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- |
| Quercetin 3-O-α-L-arabinoside |
| 3-(alpha-L-Arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl α-L-arabinopyranoside |
| Quercetin 3-O-alpha-L-arabinoside |
