Introduction：Basic information about CAS 56-47-3|Deoxycorticosterone acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.
Related Catalog
Signaling Pathways >>Metabolic Enzyme/Protease >>Mineralocorticoid ReceptorResearch Areas >>Endocrinology
Chemical & Physical Properties
Density
1.1±0.1 g/cm3
Boiling Point
504.1±50.0 °C at 760 mmHg
Melting Point
157°C
Molecular Formula
C23H32O4
Molecular Weight
372.498
Flash Point
218.0±30.2 °C
Exact Mass
372.230072
PSA
60.44000
LogP
4.53
Vapour Pressure
0.0±1.3 mmHg at 25°C
Index of Refraction
1.542
InChIKey
VPGRYOFKCNULNK-ACXQXYJUSA-N
SMILES
CC(=O)OCC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C
Storage condition
Refrigerator
Water Solubility
H2O: insoluble
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
HG0525000
CHEMICAL NAME :
11-Deoxycorticosterone, acetate
CAS REGISTRY NUMBER :
56-47-3
BEILSTEIN REFERENCE NO. :
2570798
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C23-H32-O4
MOLECULAR WEIGHT :
372.55
WISWESSER LINE NOTATION :
L E5 B666 OV MUTJ A F FV1OV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
520 mg/kg/13W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 83,14,1953 ** REPRODUCTIVE DATA **
female 56 day(s) pre-mating female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - live birth index (measured after birth)
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 120,238,1965
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
224 mg/kg
SEX/DURATION :
female 56 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 120,238,1965
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