CAS 66852-54-8|halobetasol propionate

Introduction：Basic information about CAS 66852-54-8|halobetasol propionate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. halobetasol propionate BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Synonyms

Common Name	halobetasol propionate
CAS Number	66852-54-8	Molecular Weight	484.96000
Density	0.934 g/mL at 25 °C(lit.)	Boiling Point	55 °C0.3 mm Hg(lit.)
Molecular Formula	C₂₅H₃₁ClF₂O₅	Melting Point	-32°C
MSDS	/	Flash Point	185 °F

Names

Name	Halobetasol propionate
Synonym	More Synonyms

halobetasol propionate BiologicalActivity

Description	Halobetasol propionate is a synthetic corticosteroid for topical dermatological use; exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Others

Chemical & Physical Properties

Density	0.934 g/mL at 25 °C(lit.)
Boiling Point	55 °C0.3 mm Hg(lit.)
Melting Point	-32°C
Molecular Formula	C₂₅H₃₁ClF₂O₅
Molecular Weight	484.96000
Flash Point	185 °F
Exact Mass	484.18300
PSA	80.67000
LogP	4.05110
Index of Refraction	n20/D 1.539(lit.)
InChIKey	BDSYKGHYMJNPAB-LICBFIPMSA-N
SMILES	CCC(=O)OC1(C(=O)CCl)C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC21C
Storage condition	Refrigerator

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU3723500

CHEMICAL NAME :: Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxo propoxy)-, (6-alpha,11-beta,16-beta)-

CAS REGISTRY NUMBER :: 66852-54-8

LAST UPDATED :: 199409

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C25-H31-Cl-F2-O5

MOLECULAR WEIGHT :: 485.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >15 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 27,304,1991

Safety Information

Hazard Codes	T
Risk Phrases	R22:Harmful if swallowed. R23:Toxic by inhalation. R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36-S45-S7/9
RIDADR	2810
WGK Germany	3
RTECS	BY4190000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2937229000

Customs

HS Code	2937229000

Synonyms

(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propanoate

halobetasolpropionate

halobetasol 17-propionate

(6a,11b,16b)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione

21-Chloro-6α,9-difluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate

Ultravate

Uiobetasol Propionate

Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)-

Miracorten

Halobetasol

ulobetasol propionate

propanoate de (6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(chloroacétyl)-6,9-difluoro-11-hydroxy-10,13,16-triméthyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-17-yle

(6α,11β,16β)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate

(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(Chloracetyl)-6,9-difluor-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-ylpropanoat

MFCD00866013

21-Chloro-6a,9-difluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-Propionate

(6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate

Halobetasol (propionate)

Recommended......