Introduction：Basic information about CAS 53350-26-8|5,7,3',4',5'-Pentamethoxyflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5,7,3',4',5'-Pentamethoxyflavone |
|---|
| CAS Number | 53350-26-8 | Molecular Weight | 372.36900 |
|---|
| Density | 1.244g/cm3 | Boiling Point | 554.4ºC at 760mmHg |
|---|
| Molecular Formula | C20H20O7 | Melting Point | 198-200ºC |
|---|
| MSDS | / | Flash Point | 243.5ºC |
|---|
Names
| Name | 3',4',5',5,7-Pentamethoxyflavone |
|---|
| Synonym | More Synonyms |
|---|
5,7,3',4',5'-Pentamethoxyflavone BiologicalActivity
| Description | 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Hou X, et al. 3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38(5):396-401. |
|---|
Chemical & Physical Properties
| Density | 1.244g/cm3 |
|---|
| Boiling Point | 554.4ºC at 760mmHg |
|---|
| Melting Point | 198-200ºC |
|---|
| Molecular Formula | C20H20O7 |
|---|
| Molecular Weight | 372.36900 |
|---|
| Flash Point | 243.5ºC |
|---|
| Exact Mass | 372.12100 |
|---|
| PSA | 76.36000 |
|---|
| LogP | 3.50300 |
|---|
| Index of Refraction | 1.565 |
|---|
| InChIKey | GIKVSFNAEBQLGB-UHFFFAOYSA-N |
|---|
| SMILES | COc1cc(OC)c2c(=O)cc(-c3cc(OC)c(OC)c(OC)c3)oc2c1 |
|---|
| Storage condition | 2-8°C |
|---|
Safety Information
| Safety Phrases | S22-S24/25 |
|---|
| HS Code | 2914509090 |
|---|
Customs
| HS Code | 2914509090 |
|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
|---|
Synonyms
| 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one |
