Introduction:Basic information about CAS 152743-19-6|Nebadensin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nebadensin |
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| CAS Number | 152743-19-6 | Molecular Weight | 344.315 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 615.0±55.0 °C at 760 mmHg |
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| Molecular Formula | C18H16O7 | Melting Point | / |
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| MSDS | / | Flash Point | 227.0±25.0 °C |
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Names
| Name | lysionotin |
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| Synonym | More Synonyms |
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Nebadensin BiologicalActivity
| Description | Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| Target | IC50: α-Toxin[1] |
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| References | [1]. Teng Z, et al.Lysionotin attenuates Staphylococcus aureus pathogenicity by inhibiting α-toxin expression.Appl Microbiol Biotechnol. 2017 Sep;101(17):6697-6703. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 615.0±55.0 °C at 760 mmHg |
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| Molecular Formula | C18H16O7 |
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| Molecular Weight | 344.315 |
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| Flash Point | 227.0±25.0 °C |
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| Exact Mass | 344.089600 |
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| PSA | 98.36000 |
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| LogP | 1.79 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.627 |
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Synonyms
| shidiaolanjiasu |
| Nebadensin |
| 4H-1-Benzopyran-4-one, 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)- |
| 5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| 5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one |