CAS 152743-19-6|Nebadensin

Introduction:Basic information about CAS 152743-19-6|Nebadensin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameNebadensin
CAS Number152743-19-6Molecular Weight344.315
Density1.4±0.1 g/cm3Boiling Point615.0±55.0 °C at 760 mmHg
Molecular FormulaC18H16O7Melting Point/
MSDS/Flash Point227.0±25.0 °C

Names

Namelysionotin
SynonymMore Synonyms

Nebadensin BiologicalActivity

DescriptionLysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
Target

IC50: α-Toxin[1]

References

[1]. Teng Z, et al.Lysionotin attenuates Staphylococcus aureus pathogenicity by inhibiting α-toxin expression.Appl Microbiol Biotechnol. 2017 Sep;101(17):6697-6703.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point615.0±55.0 °C at 760 mmHg
Molecular FormulaC18H16O7
Molecular Weight344.315
Flash Point227.0±25.0 °C
Exact Mass344.089600
PSA98.36000
LogP1.79
Vapour Pressure0.0±1.8 mmHg at 25°C
Index of Refraction1.627

Synonyms

shidiaolanjiasu
Nebadensin
4H-1-Benzopyran-4-one, 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-
5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
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