CAS 111-02-4|Squalene
Introduction：Basic information about CAS 111-02-4|Squalene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Squalene | ||
|---|---|---|---|
| CAS Number | 111-02-4 | Molecular Weight | 410.718 |
| Density | 0.8±0.1 g/cm3 | Boiling Point | 429.3±0.0 °C at 760 mmHg |
| Molecular Formula | C30H50 | Melting Point | −75 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 254.1±22.2 °C |
| Symbol | GHS08 | Signal Word | Danger |
Names
| Name | squalene |
|---|---|
| Synonym | More Synonyms |
Squalene BiologicalActivity
| Description | Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseResearch Areas >>InfectionNatural Products >>Terpenoids and Glycosides |
| Target | Human Endogenous Metabolite |
| References | [1]. Muzalevskaya EN, et al. SQUALENE: PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES. Eksp Klin Farmakol. 2015;78(6):30-6. |
Chemical & Physical Properties
| Density | 0.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 429.3±0.0 °C at 760 mmHg |
| Melting Point | −75 °C(lit.) |
| Molecular Formula | C30H50 |
| Molecular Weight | 410.718 |
| Flash Point | 254.1±22.2 °C |
| Exact Mass | 410.391266 |
| LogP | 13.09 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.492 |
| InChIKey | YYGNTYWPHWGJRM-AAJYLUCBSA-N |
| SMILES | CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C |
| Storage condition | 2-8°C |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 76,1021,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 76,1021,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9556 No. of Facilities: 20 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 737 (estimated) No. of Female Employees: 717 (estimated)
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H304 |
| Precautionary Statements | P301 + P310-P331 |
| Personal Protective Equipment | Eyeshields;Gloves |
| Hazard Codes | F |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | XB6010000 |
| Packaging Group | II; III |
| Hazard Class | 4.1 |
| HS Code | 29012980 |
Customs
| HS Code | 2901299090 |
|---|---|
| Summary | 2901299090 unsaturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |
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Synonyms
| Squalene, all-trans- |
| (6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene |
| (E,E,E,E)-Squalene |
| 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene |
| (all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene |
| Squalene |
| triacontahexaene |
| Spinacen |
| EINECS 203-826-1 |
| Supraene |
| MFCD00008912 |
| 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (6E,10E,14E,18E)- |
| SQUALENE OIL |
| SPINACENE |
| SQUALENE WITH GC |
| (6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene |
| Squalen |
| 2,6,10,15,19,23-Hexamethyltetracosa-(2E,6E,10E,14E,18E,22E)-2,6,10,14,18,22-hexaene |
| trans-Spinacene |
