Introduction：Basic information about CAS 33390-42-0|Gartanin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Gartanin |
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| CAS Number | 33390-42-0 | Molecular Weight | 396.433 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 644.4±55.0 °C at 760 mmHg |
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| Molecular Formula | C23H24O6 | Melting Point | / |
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| MSDS | / | Flash Point | 224.9±25.0 °C |
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Names
| Name | gartanin |
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| Synonym | More Synonyms |
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Gartanin BiologicalActivity
| Description | Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways [1]. Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells [1]. |
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| References | [1]. Gao XY, et al. Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK. Neurochem Res. 2016 Sep;41(9):2267-77. [2]. Kim MO, et al. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis. Oncol Rep. 2015 Jul;34(1):139-46. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 644.4±55.0 °C at 760 mmHg |
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| Molecular Formula | C23H24O6 |
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| Molecular Weight | 396.433 |
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| Flash Point | 224.9±25.0 °C |
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| Exact Mass | 396.157288 |
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| PSA | 111.13000 |
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| LogP | 4.51 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.656 |
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| InChIKey | OJXQLGQIDIPMTE-UHFFFAOYSA-N |
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| SMILES | CC(C)=CCc1c(O)c(CC=C(C)C)c2oc3c(O)ccc(O)c3c(=O)c2c1O |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one |
| Gartanin |
| 9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)- |
| 1,3,5,8-tetrahydroxy-2,4-bis(3-methylbut-2-enyl)xanthen-9-one |
| Gartinin |
| 1,3,5,8-Tetrahydroxy-2,4-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one |
| 9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-buten-1-yl)- |
