Introduction：Basic information about CAS 80-78-4|Solanidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Solanidine |
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| CAS Number | 80-78-4 | Molecular Weight | 397.63600 |
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| Density | 1.1g/cm3 | Boiling Point | 503.1ºC at 760 mmHg |
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| Molecular Formula | C27H43NO | Melting Point | 212-214ºC |
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| MSDS | / | Flash Point | 223.5ºC |
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Names
| Name | solanidine |
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| Synonym | More Synonyms |
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Solanidine BiologicalActivity
| Description | Solanidine is a cholestane alkaloid isolated from several potato species including Solanum demissum, Solanum acaule, and Solanum tuberosum. Solanidine can inhibit proliferation and exhibit obvious antitumor effect[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. Zhang ZD, et al. Synthesis of Demissidine and Solanidine.Org Lett. 2016 Jun 17;18(12):3038-40. |
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Chemical & Physical Properties
| Density | 1.1g/cm3 |
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| Boiling Point | 503.1ºC at 760 mmHg |
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| Melting Point | 212-214ºC |
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| Molecular Formula | C27H43NO |
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| Molecular Weight | 397.63600 |
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| Flash Point | 223.5ºC |
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| Exact Mass | 397.33400 |
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| PSA | 23.47000 |
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| LogP | 5.59290 |
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| Index of Refraction | 1.576 |
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| InChIKey | JVKYZPBMZPJNAJ-OQFNDJACSA-N |
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| SMILES | CC1CCC2C(C)C3C(CC4C5CC=C6CC(O)CCC6(C)C5CCC43C)N2C1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- WF0500000
- CHEMICAL NAME :
- Solanid-5-en-3-beta-ol
- CAS REGISTRY NUMBER :
- 80-78-4
- BEILSTEIN REFERENCE NO. :
- 0045370
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C27-H43-N-O
- MOLECULAR WEIGHT :
- 397.71
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 1800 mg/kg/3D (Continuous)
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 33,191,1995
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Safety Information
| Hazard Codes | T+: Very toxic; |
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| Risk Phrases | 23/24/25 |
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| Safety Phrases | S2-S13-S22-S45-S36-S37-S39 |
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| RIDADR | UN 1544 |
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| RTECS | WF0500000 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Synonyms
| Solanidin |
| Solatubin |
| 22R,25S-Solanidanine |
| Solatubine |
| Solanidine |
| EINECS 201-309-5 |
| Solanid-5-en-3beta-ol |
