CAS 27030-97-3|N-(4-(2-benzimidazolyl)phenyl)maleimide

Introduction:Basic information about CAS 27030-97-3|N-(4-(2-benzimidazolyl)phenyl)maleimide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-(4-(2-benzimidazolyl)phenyl)maleimide
CAS Number27030-97-3Molecular Weight289.288
Density1.4±0.1 g/cm3Boiling Point556.3±52.0 °C at 760 mmHg
Molecular FormulaC17H11N3O2Melting Point247ºC
MSDS/Flash Point290.3±30.7 °C
Symbol
GHS03, GHS05, GHS06, GHS08, GHS09
Signal WordDanger

Names

Name1-[4-(1H-benzimidazol-2-yl)phenyl]pyrrole-2,5-dione
SynonymMore Synonyms

N-(4-(2-benzimidazolyl)phenyl)maleimide BiologicalActivity

DescriptionN-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Tanaka F, et, al. Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde. Chem Commun (Camb). 2004 Aug 7;(15):1762-3.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point556.3±52.0 °C at 760 mmHg
Melting Point247ºC
Molecular FormulaC17H11N3O2
Molecular Weight289.288
Flash Point290.3±30.7 °C
Exact Mass289.085114
PSA66.06000
LogP2.12
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.742
InChIKeyNZDOXVCRXDAVII-UHFFFAOYSA-N
SMILESO=C1C=CC(=O)N1c1ccc(-c2nc3ccccc3[nH]2)cc1

Safety Information

Symbol
GHS03, GHS05, GHS06, GHS08, GHS09
Signal WordDanger
Hazard StatementsH272-H301-H312-H314-H317-H330-H334-H340-H350-H360FD-H372-H410
Precautionary StatementsP201-P210-P260-P284-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P308 + P313-P403 + P233
Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety PhrasesS22-S24/25
RIDADRUN3086 - class 6.1 - PG 1 - PIH - RQ - Toxic solids, oxidizing, n.o.s., HI: all
RTECSHX7750000
HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles19

More Articles
Conformational change accompanying formation of oligomycin-induced Na(+)-bound forms and their conversion to ADP-sensitive phosphoenzymes in Na+,K(+)-ATPase.

J. Biochem. 109(2) , 299-306, (1991)

Oligomycin reduced the fluorescence intensity of an N-(p-(2-benzimidazoly)phenyl) maleimide (BIPM) probe at Cys-964 of the alpha-chain of pig kidney Na+,K(+)-ATPase with increase in the concentration ...

Different susceptibility to phospholipase A2 treatment of the fluorescence intensity changes in the vicinity of Cys-964 and Lys-501 in the alpha-chain of probe-labeled Na+,K(+)-ATPase.

J. Biochem. 115(3) , 454-62, (1994)

Phospholipase A2 [EC 3.1.1.4] treatment of pig kidney Na+,K(+)-ATPase [EC 3.6.1.3] labeled with fluorescence probes at the alpha-chain reduced the extent of the fluorescence intensity change of an N-[...

ATP-induced dynamic fluorescence changes of a N-[p-(2-benzimidazolyl)phenyl]maleimide probe at Cys241 in the alpha-chain of pig stomach H+,K+-ATPase.

J. Biochem. 122(3) , 659-65, (1997)

H+,K+-ATPase preparations from pig stomach were modified with a sulfhydryl fluorescence reagent, N-[p-(2-benzimidazolyl)phenyl] maleimide (BIPM). The addition of ATP to the modified enzyme preparation...

Synonyms

EINECS 248-173-3
N-[4-(2-benzimidazolyl)phenyl]-maleimide
1H-Pyrrole-2,5-dione, 1-[4-(1H-benzimidazol-2-yl)phenyl]-
N-[4-(1H-benzoimidazol-2-yl)-phenyl]-maleimide
1-[4-(1H-Benzimidazol-2-yl)phenyl]-1H-pyrrole-2,5-dione
MFCD00042767
BIPM
N-[p-(2-benzimidazolyl)phenyl]maleimide
N-<p-(2-Benzimidazolyl)phenyl>maleinimid
N-(4-(2-benzimidazolyl)phenyl)maleimide
N-[4-(2-Benzimidazolyl)phenyl]maleimide
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