CAS 102280-35-3|baquiloprim
| Common Name | baquiloprim | ||
|---|---|---|---|
| CAS Number | 102280-35-3 | Molecular Weight | 308.381 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 567.9±60.0 °C at 760 mmHg |
| Molecular Formula | C17H20N6 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 297.2±32.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | baquiloprim |
|---|---|
| Synonym | More Synonyms |
baquiloprim BiologicalActivity
| Description | Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Lewicki J, et, al. Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats. Res Vet Sci. 1995 May;58(3):268-71. [2]. White DG, et, al. Comparison of danofloxacin with baquiloprim/sulphadimidine for the treatment of experimentally induced Escherichia coli diarrhoea in calves. Vet Rec. 1998 Sep 5;143(10):273-6. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 567.9±60.0 °C at 760 mmHg |
| Molecular Formula | C17H20N6 |
| Molecular Weight | 308.381 |
| Flash Point | 297.2±32.9 °C |
| Exact Mass | 308.174957 |
| PSA | 93.95000 |
| LogP | 2.32 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.719 |
| InChIKey | AIOWJIMWVFWROP-UHFFFAOYSA-N |
| SMILES | Cc1cc(Cc2cnc(N)nc2N)c2cccnc2c1N(C)C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Phrases | 22-36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| RTECS | UV8142576 |
Articles7
More Articles| Eimeria alabamensis coccidiosis in grazing calves: control by a long-acting baquiloprim/sulphadimidine bolus. Appl. Parasitol. 37(3) , 168-76, (1996) The excretion of Eimeria oocysts, the faecal dry matter and the weight gain of three groups of 12 calves, were compared during their first 20 days of grazing on a pasture known to have been contaminat... | |
| Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats. Res. Vet. Sci. 58(3) , 268-71, (1995) The pharmacokinetics of baquiloprim at a dose of 8 mg kg-1 bodyweight were determined after its intravenous and intra-ruminal administration to seven healthy female dwarf goats. After intravenous inje... | |
| Prevention of Eimeria alabamensis coccidiosis by a long-acting baquiloprim/sulphadimidine bolus. Vet. Parasitol. 74(2-4) , 143-52, (1998) Twelve calves aged 6-10 months, and 12 calves aged 10-16 months were turned out onto a permanent pasture known to have been contaminated with oocysts of Eimeria alabamensis during the previous year. T... |
Synonyms
| 5-{[8-(Dimethylamino)-7-methyl-5-quinolinyl]methyl}-2,4-pyrimidinediamine |
| baquiloprim |
| 2,4-Pyrimidinediamine, 5-[[8-(dimethylamino)-7-methyl-5-quinolinyl]methyl]- |
| 5-((2,4-Diamino-5-pyrimidinyl)methyl)-8-(dimethylamino)-7-methylquinoline |
