CAS 1016-47-3|N-Acetyltryptamine
| Common Name | N-Acetyltryptamine | ||
|---|---|---|---|
| CAS Number | 1016-47-3 | Molecular Weight | 202.25200 |
| Density | 1.164 g/cm3 | Boiling Point | 484.7ºC at 760 mmHg |
| Molecular Formula | C12H14N2O | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 246.9ºC |
Names
| Name | N-acetyltryptamine |
|---|---|
| Synonym | More Synonyms |
N-Acetyltryptamine BiologicalActivity
| Description | N-Acetyltryptamine is a partial agonist for melatonin receptors in the retina[1]. N-Acetyltryptamine is also used for determination of serotonin N-acetyl transferase activity[2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Neuronal Signaling >>Melatonin ReceptorSignaling Pathways >>GPCR/G Protein >>Melatonin ReceptorResearch Areas >>Neurological Disease |
| References | [1]. Sugden D, et al. Melatonin receptor pharmacology: toward subtype specificity. Biol Cell. 1997 Nov;89(8):531-7. [2]. De Angelis J, et al. Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87). J Biol Chem. 1998 Jan 30;273(5):3045-50. |
Chemical & Physical Properties
| Density | 1.164 g/cm3 |
|---|---|
| Boiling Point | 484.7ºC at 760 mmHg |
| Molecular Formula | C12H14N2O |
| Molecular Weight | 202.25200 |
| Flash Point | 246.9ºC |
| Exact Mass | 202.11100 |
| PSA | 44.89000 |
| LogP | 2.23740 |
| Vapour Pressure | 1.51E-09mmHg at 25°C |
| Index of Refraction | 1.619 |
| InChIKey | NVUGEQAEQJTCIX-UHFFFAOYSA-N |
| SMILES | CC(=O)NCCc1c[nH]c2ccccc12 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles24
More Articles| Chloroplastic and cytoplasmic overexpression of sheep serotonin N-acetyltransferase in transgenic rice plants is associated with low melatonin production despite high enzyme activity. J. Pineal Res. 58(4) , 461-9, (2015) Serotonin N-acetyltransferase (SNAT), the penultimate enzyme in melatonin biosynthesis, catalyzes the conversion of serotonin into N-acetylserotonin. Plant SNAT is localized in chloroplasts. To test S... | |
| Serine residues 110 and 114 are required for agonist binding but not antagonist binding to the melatonin MT(1) receptor. Biochem. Biophys. Res. Commun. 282(5) , 1229-36, (2001) Site-directed mutation of serine 110 (Ser(3.35)) and serine 114 (Ser(3.39)) in the human melatonin MT(1) receptor to alanine residues reduced ligand binding affinities of seven known melatonin recepto... | |
| [The biosynthesis of low-molecular-weight nitrogen-containing secondary metabolite-alkaloids by the resident strains of Penicillium chrysogenum and Penicillium expansum isolated on the board of the Mir space station ]. Mikrobiologiia 71(6) , 773-7, (2002) The analysis of the absorption spectra of the low-molecular-weight nitrogen-containing secondary metabolites--alkaloids--of 4 Penicillium chrysogenum strains and 6 Penicillium expansum strains isolate... |
Synonyms
| N-[2-(1H-indol-3-yl)ethyl]acetamide |
| Tocris-0357 |
| Chicago Sky Blue 6B |
| N-Acetyltryptamine |
| N-(2-(1H-Indol-3-yl)ethyl)acetamide |
