CAS 32981-85-4|Bz-RS-iSer(3-Ph)-OMe

Introduction:Basic information about CAS 32981-85-4|Bz-RS-iSer(3-Ph)-OMe, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBz-RS-iSer(3-Ph)-OMe
CAS Number32981-85-4Molecular Weight299.321
Density1.2±0.1 g/cm3Boiling Point540.3±50.0 °C at 760 mmHg
Molecular FormulaC17H17NO4Melting Point/
MSDS/Flash Point280.6±30.1 °C

Names

Namemethyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate
SynonymMore Synonyms

Bz-RS-iSer(3-Ph)-OMe BiologicalActivity

DescriptionBz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1].
Related CatalogSignaling Pathways >>Anti-infection >>HIVResearch Areas >>Infection
References

[1]. Krawczyk E, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005;57(6):791‐797.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point540.3±50.0 °C at 760 mmHg
Molecular FormulaC17H17NO4
Molecular Weight299.321
Flash Point280.6±30.1 °C
Exact Mass299.115753
PSA75.63000
LogP2.90
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.588
InChIKeyUYJLJICUXJPKTB-GJZGRUSLSA-N
SMILESCOC(=O)C(O)C(NC(=O)c1ccccc1)c1ccccc1
Storage condition-20℃

Safety Information

HS Code2924299090

Customs

HS Code2924299090
Summary2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
Methyl (2R,3S)-N-Benzoyl-3-Phenylisoserine
Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βS)-
MFCD00673331
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