CAS 72909-34-3|pyrroloquinoline quinone
| Common Name | pyrroloquinoline quinone | ||
|---|---|---|---|
| CAS Number | 72909-34-3 | Molecular Weight | 330.206 |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 1018.6±65.0 °C at 760 mmHg |
| Molecular Formula | C14H6N2O8 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 569.8±34.3 °C |
Names
| Name | pyrroloquinoline quinone |
|---|---|
| Synonym | More Synonyms |
pyrroloquinoline quinone BiologicalActivity
| Description | Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/Immunology |
| Target | Human Endogenous Metabolite |
| In Vitro | Mouse pups born to and nursing from Pyrroloquinoline quinone (PQQ)-deprived dams have a compromised immune response as well as alopecia, a hunched posture, and a susceptibility to aortic aneurysms[2]. |
| References | [1]. Moog RS, et al. Evidence for methoxatin (pyrroloquinolinequinone) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy. Proc Natl Acad Sci U S A. 1986 Nov;83(22):8435-9. [2]. Bishop A, et al. Methoxatin (PQQ) in guinea-pig neutrophils. Free Radic Biol Med. 1994 Oct;17(4):311-20. |
Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 1018.6±65.0 °C at 760 mmHg |
| Molecular Formula | C14H6N2O8 |
| Molecular Weight | 330.206 |
| Flash Point | 569.8±34.3 °C |
| Exact Mass | 330.012421 |
| PSA | 174.72000 |
| LogP | -0.65 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.801 |
| InChIKey | MMXZSJMASHPLLR-UHFFFAOYSA-N |
| SMILES | O=C(O)c1cc(C(=O)O)c2c(n1)C(=O)C(=O)c1cc(C(=O)O)[nH]c1-2 |
| Storage condition | 2-8°C |
| Stability | Light and Temperature Sensitive |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles50
More Articles| Molecular-level characterization of elastin-like constructs and human aortic elastin Matrix Biol. 38 , 12-21, (2014) This study aimed to characterize the structures of two elastin-like constructs, one composed of a cross-linked elastin-like polypeptide and the other one of cross-linked tropoelastin, and native aorti... | |
| Genome-wide RNA sequencing analysis of quorum sensing-controlled regulons in the plant-associated Burkholderia glumae PG1 strain. Appl. Environ. Microbiol. 81 , 7993-8007, (2015) Burkholderia glumae PG1 is a soil-associated motile plant-pathogenic bacterium possessing a cell density-dependent regulation system called quorum sensing (QS). Its genome contains three genes, here d... | |
| Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE 10(3) , e0121939, (2015) Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver injuries, and its progression toward cirrhosis is the major cause of liver-related morbidity and morta... |
Synonyms
| MFCD00043125 |
| coenzyme PQQ |
| 2,7,9-Tricarboxy-1H-pyrrolo(2,3-f)quinoline-4,5-dione |
| PQQ Cofactor |
| Pyrroloquinoline-quinone |
| 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid |
| 4,5-dihydro-4,5-dioxo-1H-pyrrolo-[2,3-f]quinoline-2,7,9-tricarboxylic acid |
| 1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo- |
| methoxanthin |
| 4,5-Dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid |
| PQQ |
| Pyrroloquinoline quinone |
| 2,7,9-Tricarboxy-4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline |
| Methoxatin |
| 1H-Pyrrolo[2,3-f]quinolin-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo- |
| 1H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo- |
