CAS 7412-78-4|β-Endorphin (30-31) (human)
| Common Name | β-Endorphin (30-31) (human) | ||
|---|---|---|---|
| CAS Number | 7412-78-4 | Molecular Weight | 204.181 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 536.6±50.0 °C at 760 mmHg |
| Molecular Formula | C7H12N2O5 | Melting Point | 155-158ºC (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 278.3±30.1 °C |
Names
| Name | (2S)-2-[(2-aminoacetyl)amino]pentanedioic acid |
|---|---|
| Synonym | More Synonyms |
β-Endorphin (30-31) (human) BiologicalActivity
| Description | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>AChE |
| Target | Acetylcholinesterase |
| References | [1]. Koelle GB, et al. Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo. Proc Natl Acad Sci U S A. 1985 Aug;82(15):5213-7. [2]. Yourick JJ, et al. Regeneration of acetylcholinesterase in clonal neuroblastoma-glioma hybrid NG108-15 cells after soman inhibition: effect of glycyl-L-glutamine. Cell Biol Toxicol. 1991 Jul;7(3):229-37. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 536.6±50.0 °C at 760 mmHg |
| Melting Point | 155-158ºC (dec.)(lit.) |
| Molecular Formula | C7H12N2O5 |
| Molecular Weight | 204.181 |
| Flash Point | 278.3±30.1 °C |
| Exact Mass | 204.074615 |
| PSA | 129.72000 |
| LogP | -2.68 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.537 |
| InChIKey | IEFJWDNGDZAYNZ-BYPYZUCNSA-N |
| SMILES | NCC(=O)NC(CCC(=O)O)C(=O)O |
| Storage condition | −20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924199090 |
Customs
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| L-Glutamic acid, N-glycyl- |
| N-glycylglutamic acid |
| H2N-glycine-Acide glutamique-OH |
| EINECS 231-019-4 |
| H-Gly-Glu-OH |
| Glycylglutamic acid |
| Gly-L-Glu-OH |
| L-Glutamic acid,N-glycyl |
| GLY-GLU |
| MFCD00008128 |
| Glycyl-L-glutamic acid |
| L-Glutamic acid, glycyl- |
| N-glycyl-L-glutamic acid |
| Gly-Glu-OH |
