CAS 106-25-2|cis-3,7-Dimethyl-2,6-octadien-1-ol

[1]. Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca²⁺ overload in saprotrophic fungus Aspergillus flavus. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672.

[2]. Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca²⁺ and ROS in Candida albicans. Int J Biochem Cell Biol. 2017 Apr;85:114-122.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

RG5840000

CHEMICAL NAME :

2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)-

CAS REGISTRY NUMBER :

106-25-2

LAST UPDATED :

199709

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C10-H18-O

MOLECULAR WEIGHT :

154.28

WISWESSER LINE NOTATION :

Q2UY1&3UY1&1 -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,623,1976 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,623,1976

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6. Volume(issue)/page/year: 21,342,1962

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

>5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,623,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9625 No. of Facilities: 1991 (estimated) No. of Industries: 4 No. of Occupations: 9 No. of Employees: 13881 (estimated) No. of Female Employees: 7957 (estimated)

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