CAS 200937-57-1|n-(9-fluorenylmethoxycarbonyl)-l-leucin&

Introduction：Basic information about CAS 200937-57-1|n-(9-fluorenylmethoxycarbonyl)-l-leucin&, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. n-(9-fluorenylmethoxycarbonyl)-l-leucin& BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	n-(9-fluorenylmethoxycarbonyl)-l-leucin&
CAS Number	200937-57-1	Molecular Weight	354.41
Density	/	Boiling Point	/
Molecular Formula	C₂₁H₂₃₁₅NO₄	Melting Point	152-156ºC(lit.)
MSDS	ChineseUSA	Flash Point	/

Names

Name	N-(9-Fluorenylmethoxycarbonyl)-L-leucine-15N
Synonym	More Synonyms

n-(9-fluorenylmethoxycarbonyl)-l-leucin& BiologicalActivity

Description	Fmoc-leucine-15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence
Related Catalog	Signaling Pathways >>Cell Cycle/DNA Damage >>TopoisomeraseSignaling Pathways >>Anti-infection >>HCVResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>SARS-CoV
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-242. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-242.

Chemical & Physical Properties

Melting Point	152-156ºC(lit.)
Molecular Formula	C₂₁H₂₃₁₅NO₄
Molecular Weight	354.41
Exact Mass	354.16000
PSA	75.63000
LogP	4.41530
InChIKey	CBPJQFCAFFNICX-VIKCBUFNSA-N
SMILES	CC(C)CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3

Synonyms

L-Leucine-15N,N-Fmoc

Fmoc-Leu-OH-15N

MFCD00209748

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