Introduction：Basic information about CAS 20110-59-2|Glycine-1-13C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Glycine-1-13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
Chemical & Physical Properties
Density
1.254g/cm3
Melting Point
240ºC (dec.)(lit.)
Molecular Formula
C13CH5NO2
Molecular Weight
76.05930
Exact Mass
76.03540
PSA
63.32000
Index of Refraction
1.46
InChIKey
DHMQDGOQFOQNFH-VQEHIDDOSA-N
SMILES
NCC(=O)O
Safety Information
RIDADR
NONH for all modes of transport
WGK Germany
3
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