Introduction：Basic information about CAS 41372-02-5|Penicillin G benzathine tetrahydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Penicillin G benzathine tetrahydrate |
|---|
| CAS Number | 41372-02-5 | Molecular Weight | 981.185 |
|---|
| Density | / | Boiling Point | 1299.8ºC at 760 mmHg |
|---|
| Molecular Formula | C48H64N6O12S2 | Melting Point | 123-124°C |
|---|
| MSDS | / | Flash Point | 739.9ºC |
|---|
Names
| Name | N,N'-dibenzylethane-1,2-diamine,(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,tetrahydrate |
|---|
| Synonym | More Synonyms |
|---|
Penicillin G benzathine tetrahydrate BiologicalActivity
| Description | Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is an antibiotic against many bacterial infections[1]. |
|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
|---|
| In Vivo | Penicillin G benzathine tetrahydrate displays activity and antibacterial effect in CD-I mice infected with Staphylococcus aureus Smith[2]. |
|---|
| References | [1]. Bowen AC, et al. Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial. Lancet. 2014 Dec 13;384(9960):2132-40. [2]. J A Yurchenco, et al. Substituted Penicillin Amides. Duration of Antibacterial Activity (Depot Effect) in Experimental Infections in Mice. Chemotherapy . 1972;17(6):405-15. |
|---|
Chemical & Physical Properties
| Boiling Point | 1299.8ºC at 760 mmHg |
|---|
| Melting Point | 123-124°C |
|---|
| Molecular Formula | C48H64N6O12S2 |
|---|
| Molecular Weight | 981.185 |
|---|
| Flash Point | 739.9ºC |
|---|
| Exact Mass | 980.402344 |
|---|
| PSA | 285.00000 |
|---|
| LogP | 5.46980 |
|---|
| InChIKey | WIDKTXGNSOORHA-CJHXQPGBSA-N |
|---|
| SMILES | CC1(C)SC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O.CC1(C)SC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O.O.O.O.O.c1ccc(CNCCNCc2ccccc2)cc1 |
|---|
Safety Information
| Hazard Codes | Xi |
|---|
| Risk Phrases | 42/43 |
|---|
| Safety Phrases | 22-36/37-45-24/25 |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| HS Code | 2941109900 |
|---|
Customs
Synonyms
| Penicillin G Benzathine Tetrahydrate |
| (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsäure--N,N'-dibenzylethan-1,2-diamin(2:1)tetrahydrat |
| acide (2S,5R,6R)-3,3-diméthyl-7-oxo-6-[(phénylacétyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique - N,N'-dibenzyléthane-1,2-diamine (2:1) tétrahydrate |
| (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzyl-1,2-ethanediamine hydrate (2:1:4) |
| 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, (2S,5R,6R)-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine, hydrate (2:1:4) |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-, (2S,5R,6R)-, compd. with N,N-bis(phenylmethyl)-1,2-ethanediamine, hydrate (2:1:4) |
| (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine (2:1) tetrahydrate |
