CAS 4178-93-2|N-(4-Nitrophenyl)-L-leucinamide
Introduction：Basic information about CAS 4178-93-2|N-(4-Nitrophenyl)-L-leucinamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-(4-Nitrophenyl)-L-leucinamide | ||
|---|---|---|---|
| CAS Number | 4178-93-2 | Molecular Weight | 251.282 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 454.5±30.0 °C at 760 mmHg |
| Molecular Formula | C12H17N3O3 | Melting Point | 88-90ºC |
| MSDS | ChineseUSA | Flash Point | 228.7±24.6 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | L-Leucine-p-nitroanilide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 454.5±30.0 °C at 760 mmHg |
| Melting Point | 88-90ºC |
| Molecular Formula | C12H17N3O3 |
| Molecular Weight | 251.282 |
| Flash Point | 228.7±24.6 °C |
| Exact Mass | 251.126984 |
| PSA | 100.94000 |
| LogP | 1.83 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.589 |
| InChIKey | AXZJHDNQDSVIDR-NSHDSACASA-N |
| SMILES | CC(C)CC(N)C(=O)Nc1ccc([N+](=O)[O-])cc1 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H319 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36 |
| Safety Phrases | S26-S36-S37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924299090 |
Customs
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles27
More Articles| Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18. PLoS ONE 10(2) , e0115859, (2015) Malaria is a parasitic disease that remains a global health burden. The ability of the parasite to rapidly develop resistance to therapeutics drives an urgent need for the delivery of new drugs. The M... | |
| Beta-phenyl cysteine: a leucine aminopeptidase inhibitor. Pharmacol. Res. Commun. 16(6) , 533-8, (1984) Beta-phenyl cysteine: a leucine aminopeptidase inhibitor. The kinetic parameters of the inhibition of the leucine aminopeptidase by beta-phenyl cysteine are reported in this communication. | |
| Exploration of structural and physicochemical requirements and search of virtual hits for aminopeptidase N inhibitors. Mol. Divers. 17(1) , 123-37, (2013) Aminopeptidase N (APN) inhibitors have been reported to be effective in treating of life threatening diseases including cancer. Validated ligand- and structure-based pharmacophore mapping approaches w... |
Synonyms
| MFCD00063681 |
| EINECS 224-047-3 |
| Pentanamide, 2-amino-4-methyl-N-(4-nitrophenyl)-, (2S)- |
| N-(4-Nitrophenyl)-L-leucinamide |
| h-leu-pna |
