Introduction：Basic information about CAS 4350-07-6|(R)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (R)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID |
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| CAS Number | 4350-07-6 | Molecular Weight | 220.22500 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C11H12N2O3 | Melting Point | 27ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-hydroxy-D-tryptophan |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | D-5-Hydroxytryptophan (D-5-HTP) is the D-isomers of 5-HTP, and can be isolated from DL-5-hydroxytryptophan by successive separations[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. J Arendt, et al. Alternative pathways of 5-hydroxyindole metabolism. II. The role transamination in the metabolism of D-5-hydroxytryptophan in the rat. Biochem Pharmacol. 1967 Mar;16(3):419-22. |
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Chemical & Physical Properties
| Melting Point | 27ºC |
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| Molecular Formula | C11H12N2O3 |
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| Molecular Weight | 220.22500 |
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| Exact Mass | 220.08500 |
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| PSA | 99.34000 |
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| LogP | 1.52820 |
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| InChIKey | LDCYZAJDBXYCGN-SECBINFHSA-N |
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| SMILES | NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- YN7050000
- CHEMICAL NAME :
- Tryptophan, 5-hydroxy-, D-
- CAS REGISTRY NUMBER :
- 4350-07-6
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C11-H12-N2-O3
- MOLECULAR WEIGHT :
- 220.25
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973
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Safety Information
| Hazard Codes | Xn,Xi |
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| Risk Phrases | 20/21-20/21/22-36/37/38-65 |
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| Safety Phrases | 26-36 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| (2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid |
| Tryptophan,5-hydroxy-,D |
| D-5-HTP (D-2-Amino-3-(5-hydroxyindolyl)propionic acid |
| C11H12N2O3 |
| 5-Hydroxytryptophan D-form |
| HRP |
| D-Tryptophan,5-hydroxy |
| D-5-Hydroxytryptophan |
