Introduction:Basic information about CAS 4669-23-2|Triethylene glycol monodecyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Triethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target
PEGs
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Chemical & Physical Properties
Density
0.936 g/mL at 20ºC(lit.)
Molecular Formula
C16H34O4
Molecular Weight
290.43900
Exact Mass
290.24600
PSA
47.92000
LogP
3.16920
Index of Refraction
n20/D 1.449
InChIKey
UKODLHVFJRCQME-UHFFFAOYSA-N
SMILES
CCCCCCCCCCOCCOCCOCCO
Storage condition
2-8°C
Safety Information
Personal Protective Equipment
Eyeshields;Gloves
Safety Phrases
24/25
RIDADR
NONH for all modes of transport
WGK Germany
3
Articles2
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