CAS 4669-23-2|Triethylene glycol monodecyl ether

Introduction:Basic information about CAS 4669-23-2|Triethylene glycol monodecyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTriethylene glycol monodecyl ether
CAS Number4669-23-2Molecular Weight290.43900
Density0.936 g/mL at 20ºC(lit.)Boiling Point/
Molecular FormulaC16H34O4Melting Point/
MSDSChineseUSAFlash Point/

Names

Name2-[2-(2-decoxyethoxy)ethoxy]ethanol
SynonymMore Synonyms

Triethylene glycol monodecyl ether BiologicalActivity

DescriptionTriethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Chemical & Physical Properties

Density0.936 g/mL at 20ºC(lit.)
Molecular FormulaC16H34O4
Molecular Weight290.43900
Exact Mass290.24600
PSA47.92000
LogP3.16920
Index of Refractionn20/D 1.449
InChIKeyUKODLHVFJRCQME-UHFFFAOYSA-N
SMILESCCCCCCCCCCOCCOCCOCCO
Storage condition2-8°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves
Safety Phrases24/25
RIDADRNONH for all modes of transport
WGK Germany3

Articles2

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Synonyms

Decyltriglycol
Triethylene glycol monodecyl ether
triethylene glycol monodecyl ether
Emulgin BL 309
C10E3
3,6,9-trioxa-1-nonadecanol
n-decyl triethylene glycol monoether
Triethyleneglycol monodecyl ether solution
triethylene glycol mono-n-decyl ether
Decyl triethylene glycol ether
Triethyleneglycol monodecyl ether 1 mM solution
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