Introduction：Basic information about CAS 171745-13-4|4-(3-bromoanilino)-6,7-diethoxyquinazoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-(3-bromoanilino)-6,7-diethoxyquinazoline |
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| CAS Number | 171745-13-4 | Molecular Weight | 388.26 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 492.6±45.0 °C at 760 mmHg |
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| Molecular Formula | C18H18BrN3O2 | Melting Point | / |
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| MSDS | / | Flash Point | 251.7±28.7 °C |
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Names
| Name | N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>JAK/STAT Signaling >>EGFRSignaling Pathways >>Protein Tyrosine Kinase/RTK >>EGFR |
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| Target | EGFR:10.6 (pIC50) |
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| References | [1]. Farhan Ahmad Pasha, et al. In silico QSAR studies of anilinoquinolines as EGFR inhibitors. J Mol Model. 2010 Feb;16(2):263-77. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 492.6±45.0 °C at 760 mmHg |
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| Molecular Formula | C18H18BrN3O2 |
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| Molecular Weight | 388.26 |
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| Flash Point | 251.7±28.7 °C |
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| Exact Mass | 387.058228 |
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| PSA | 56.27000 |
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| LogP | 5.14 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.652 |
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| InChIKey | YXOXHAUUTIOBDA-UHFFFAOYSA-N |
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| SMILES | CCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCC |
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Safety Information
Synonyms
| compound 56 |
| N-(3-Bromophenyl)-6,7-diethoxyquinazolin-4-amine |
| 4-(3'-bromoanilino)-6,7-diethoxyquinazoline |
| 4-(3-bromoanilino)-6,7-diethoxyquinazoline |
| 4-quinazolinamine, N-(3-bromophenyl)-6,7-diethoxy- |
| N-(3-Bromophenyl)-6,7-diethoxy-4-quinazolinamine |
| 4-[(3-bromophenyl)amino]-6,7-diethoxyquinazoline |
| (3-Bromophenyl)-(6,7-diethoxyquinazolin-4-yl)-amine |
| YXOXHAUUTIOBDA-UHFFFAOYSA |
