Introduction：Basic information about CAS 483-17-0|Cephaeline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cephaeline |
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| CAS Number | 483-17-0 | Molecular Weight | 466.61200 |
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| Density | 1.21g/cm3 | Boiling Point | 614ºC at 760mmHg |
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| Molecular Formula | C28H38N2O4 | Melting Point | 115-116ºC |
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| MSDS | / | Flash Point | 325.1ºC |
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Names
| Name | cephaeline |
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| Synonym | More Synonyms |
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Cephaeline BiologicalActivity
| Description | Cephaeline is a phenolic alkaloid in Indian Ipecac roots. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
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| References | [1]. N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529. [2]. Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31. |
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Chemical & Physical Properties
| Density | 1.21g/cm3 |
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| Boiling Point | 614ºC at 760mmHg |
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| Melting Point | 115-116ºC |
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| Molecular Formula | C28H38N2O4 |
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| Molecular Weight | 466.61200 |
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| Flash Point | 325.1ºC |
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| Exact Mass | 466.28300 |
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| PSA | 63.19000 |
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| LogP | 4.90710 |
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| Vapour Pressure | 1.15E-15mmHg at 25°C |
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| Index of Refraction | 1.614 |
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| InChIKey | DTGZHCFJNDAHEN-OZEXIGSWSA-N |
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| SMILES | CCC1CN2CCc3cc(OC)c(OC)cc3C2CC1CC1NCCc2cc(O)c(OC)cc21 |
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| Storage condition | -20℃ |
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Safety Information
| Hazard Codes | T+ |
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| RIDADR | UN 1544 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Synonyms
| Cephaeline |
| (1'β)-7',10,11-Trimethoxyemetan-6'-ol |
| 10,11,7'-Trimethoxy-emetan-6'-ol |
