CAS 7413-36-7|nifenalol

Introduction:Basic information about CAS 7413-36-7|nifenalol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namenifenalol
CAS Number7413-36-7Molecular Weight224.26
Density1.173g/cm3Boiling Point377.4ºC at 760 mmHg
Molecular FormulaC11H16N2O3Melting Point/
MSDS/Flash Point182ºC

Names

Name2-(Isopropylamino)-1-(4-nitrophenyl)ethanol
SynonymMore Synonyms

nifenalol BiologicalActivity

DescriptionNifenalol is a β-adrenergic receptor blocker. Nifenalol inhibits β-adrenoceptor differentiation in right atrium, diaphragm and adipose tissue in a rat model[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor
Target

Beta-1 adrenergic receptor

References

[1]. Harms HH, et al. Differentiation of beta-adrenoceptors in right atrium, diaphragm and adipose tissue of the rat, using stereoisomers of propranolol, alprenolol, nifenalol and practolol. Life Sci. 1977 Jul 1;21(1):123-8.  

Chemical & Physical Properties

Density1.173g/cm3
Boiling Point377.4ºC at 760 mmHg
Molecular FormulaC11H16N2O3
Molecular Weight224.26
Flash Point182ºC
Exact Mass224.11600
PSA78.08000
LogP2.54030
Index of Refraction1.555
InChIKeyUAORFCGRZIGNCI-UHFFFAOYSA-N
SMILESCC(C)NCC(O)c1ccc([N+](=O)[O-])cc1

Synonyms

Methanesulfonamide,N-[4-[(1R)-2-chloro-1-hydroxyethyl]phenyl]
(R)-2-isopropylamino-1-(4-nitro-phenyl)-ethanol
2-chloro-1-(4'-methanesulfonamidophenyl)ethanol
N-{4-[(1R)-2-chloro-1-hydroxyethyl]phenyl}methanesulfonamide
(R)-(-)-N-[4-(1-hydroxy-2-chloroethyl)phenyl]methanesulfonamide
(R)-nifenalol
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