CAS 1015855-75-0|imidacloprid d4 (imidazolidin-4,4,5,5 d4)
| Common Name | imidacloprid d4 (imidazolidin-4,4,5,5 d4) | ||
|---|---|---|---|
| CAS Number | 1015855-75-0 | Molecular Weight | 259.686 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 442.3±55.0 °C at 760 mmHg |
| Molecular Formula | C9H6ClD4N5O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 221.3±31.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | N-[1-[(6-chloropyridin-3-yl)methyl]-4,4,5,5-tetradeuterioimidazol-2-yl]nitramide |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Imidacloprid-d4 is the deuterium labeled Imidacloprid[1]. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton[2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>Others |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Kim J, et al. Imidacloprid, a neonicotinoid insecticide, induces insulin resistance. J Toxicol Sci. 2013;38(5):655-60. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 442.3±55.0 °C at 760 mmHg |
| Molecular Formula | C9H6ClD4N5O2 |
| Molecular Weight | 259.686 |
| Flash Point | 221.3±31.5 °C |
| Exact Mass | 259.077423 |
| PSA | 86.34000 |
| LogP | -0.43 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.706 |
| InChIKey | YWTYJOPNNQFBPC-KHORGVISSA-N |
| SMILES | O=[N+]([O-])NC1=NCCN1Cc1ccc(Cl)nc1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
Articles4
More Articles| Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 969 , 85-94, (2014) A rapid and sensitive analytical method was developed for simultaneous determination of eight neonicotinoid insecticides (acetamiprid, clothianidin, dinotefuran, flonicamid, imidacloprid, nitenpyram, ... | |
| Biological Monitoring of Human Exposure to Neonicotinoids Using Urine Samples, and Neonicotinoid Excretion Kinetics. PLoS ONE 11 , e0146335, (2016) Neonicotinoids, which are novel pesticides, have entered into usage around the world because they are selectively toxic to arthropods and relatively non-toxic to vertebrates. It has been suggested tha... | |
| Widespread occurrence of neonicotinoid insecticides in streams in a high corn and soybean producing region, USA. Environ. Pollut. 193 , 189-96, (2014) Neonicotinoid insecticides are of environmental concern, but little is known about their occurrence in surface water. An area of intense corn and soybean production in the Midwestern United States was... |
Synonyms
| 1H-Imidazol-4,5-d-2-amine, 1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydro-d-N-nitro- |
| Imidacloprid-d4 |
| Imidazolidin-4,4,5,5-d4 |
| 1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro(H)-4,5-dihydro-1H-imidazol-2-amine |
