Introduction：Basic information about CAS 225120-65-0|Cathepsin Inhibitor 1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cathepsin Inhibitor 1 |
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| CAS Number | 225120-65-0 | Molecular Weight | 401.89000 |
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| Density | 1.23±0.1 g/cm3 (20 ºC 760 Torr) | Boiling Point | / |
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| Molecular Formula | C20H24ClN5O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3-Chloro-N-(cyanomethyl)-Nα-{[1-methyl-3-(2-methyl-2-propanyl)-1H -pyrazol-5-yl]carbonyl}-L-phenylalaninamide |
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| Synonym | More Synonyms |
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Cathepsin Inhibitor 1 BiologicalActivity
| Description | Cathepsin inhibitor 1 (compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Cathepsin |
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| References | [1]. Asaad N, et, al. Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3. |
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Chemical & Physical Properties
| Density | 1.23±0.1 g/cm3 (20 ºC 760 Torr) |
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| Molecular Formula | C20H24ClN5O2 |
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| Molecular Weight | 401.89000 |
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| Exact Mass | 401.16200 |
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| PSA | 106.79000 |
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| LogP | 3.76698 |
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| InChIKey | MZRVIHRERYCHBL-HNNXBMFYSA-N |
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| SMILES | Cn1nc(C(C)(C)C)cc1C(=O)NC(Cc1cccc(Cl)c1)C(=O)NCC#N |
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| Storage condition | -20℃ |
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Safety Information
Synonyms
