CAS 520-32-1|Tricin

Introduction：Basic information about CAS 520-32-1|Tricin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Tricin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Tricin
CAS Number	520-32-1	Molecular Weight	330.289
Density	1.5±0.1 g/cm3	Boiling Point	598.5±50.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₄O₇	Melting Point	/
MSDS	/	Flash Point	224.0±23.6 °C

Names

Name	3',5'-di-O-methyltricetin
Synonym	More Synonyms

Tricin BiologicalActivity

Description	Tricin is a natural flavonoid present in large amounts in rice bran. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3].
Related Catalog	Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>CMV
References	[1]. Itoh A, et al. Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus. Microbiol Immunol. 2018 May;62(5):341-347. [2]. Sadanari H, et al. The anti-human cytomegalovirus drug tricin inhibits cyclin-dependent kinase 9. FEBS Open Bio. 2018 Feb 20;8(4):646-654. [3]. Chung DJ, et al. Inhibition of the Proliferation and Invasion of C6 Glioma Cells by Tricin via the Upregulation of Focal-Adhesion-Kinase-Targeting MicroRNA-7. J Agric Food Chem. 2018 Jul 5;66(26):6708-6716.

Description

Tricin is a natural flavonoid present in large amounts in rice bran. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3].

Related Catalog

Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>CMV

References

[1]. Itoh A, et al. Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus. Microbiol Immunol. 2018 May;62(5):341-347.

[2]. Sadanari H, et al. The anti-human cytomegalovirus drug tricin inhibits cyclin-dependent kinase 9. FEBS Open Bio. 2018 Feb 20;8(4):646-654.

[3]. Chung DJ, et al. Inhibition of the Proliferation and Invasion of C6 Glioma Cells by Tricin via the Upregulation of Focal-Adhesion-Kinase-Targeting MicroRNA-7. J Agric Food Chem. 2018 Jul 5;66(26):6708-6716.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	598.5±50.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₄O₇
Molecular Weight	330.289
Flash Point	224.0±23.6 °C
Exact Mass	330.073944
PSA	109.36000
LogP	1.39
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.671
InChIKey	HRGUSFBJBOKSML-UHFFFAOYSA-N
SMILES	COc1cc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc(OC)c1O

Safety Information

Hazard Codes	Xi
HS Code	2914509090

Customs

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Synonyms

Tricetin 3',5'-di-methyl ether

5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one

3',5'-DIMETHOXY-4',5,7-TRIHYDROXYFLAVONE

5,7,4'-trihydroxy-3',5'-dimethoxyflavone

Tricin

4',5,7-trihydroxy-3',5'-dimethoxyflavone

3',5'-O-dimethyltricetin

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-

5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromen-4-one

3',5'-di-O-methyltricetin

5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-chromen-4-one

tricetine-3',5'-dimethyl ether

Recommended......