CAS 223488-57-1|Evatanepag

Introduction：Basic information about CAS 223488-57-1|Evatanepag, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Evatanepag BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Evatanepag
CAS Number	223488-57-1	Molecular Weight	468.565
Density	1.3±0.1 g/cm3	Boiling Point	660.2±65.0 °C at 760 mmHg
Molecular Formula	C₂₅H₂₈N₂O₅S	Melting Point	/
MSDS	/	Flash Point	353.0±34.3 °C

Names

Name	2-[3-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]phenoxy]acetic acid
Synonym	More Synonyms

Evatanepag BiologicalActivity

Description	Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.IC50 value: 0.3 nM (EC50)Target PGE2in vitro: CP-533536 is a potent and selective EP2agonist. CP-533536 demonstrates the ability to heal fractures when administered locally as a single dose in rat models of fracture healing. CP-533536 demonstrates excellent in vitro potency against EP2 and selectivity against a broad panel of other targets.
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Prostaglandin ReceptorResearch Areas >>Cardiovascular Disease
References	[1]. Cameron KO, et al. Discovery of CP-533536: an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. Bioorg Med Chem Lett. 2009 Apr 1;19(7):2075-8.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	660.2±65.0 °C at 760 mmHg
Molecular Formula	C₂₅H₂₈N₂O₅S
Molecular Weight	468.565
Flash Point	353.0±34.3 °C
Exact Mass	468.171906
PSA	105.18000
LogP	4.78
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.600
InChIKey	WOHRHWDYFNWPNG-UHFFFAOYSA-N
SMILES	CC(C)(C)c1ccc(CN(Cc2cccc(OCC(=O)O)c2)S(=O)(=O)c2cccnc2)cc1
Storage condition	2-8℃

Synonyms

CP-533536

UNII-L266R6E31E

[3-({[4-(2-Methyl-2-propanyl)benzyl](3-pyridinylsulfonyl)amino}methyl)phenoxy]acetic acid

Acetic acid, 2-[3-[[[[4-(1,1-dimethylethyl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]phenoxy]-

evatanepag

CP533536

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