CAS 60820-94-2|Esculentoside B

Introduction：Basic information about CAS 60820-94-2|Esculentoside B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Esculentoside B BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Esculentoside B
CAS Number	60820-94-2	Molecular Weight	664.82
Density	1.3±0.1 g/cm3	Boiling Point	779.3±60.0 °C at 760 mmHg
Molecular Formula	C₃₆H₅₆O₁₁	Melting Point	/
MSDS	/	Flash Point	237.0±26.4 °C

Names

Name	Phytolaccoside B
Synonym	More Synonyms

Esculentoside B BiologicalActivity

Description	Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological DiseaseSignaling Pathways >>MAPK/ERK Pathway >>JNKSignaling Pathways >>Neuronal Signaling >>AChE
References	[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163. [2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777. [3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725.

Description

Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].

Related Catalog

Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological DiseaseSignaling Pathways >>MAPK/ERK Pathway >>JNKSignaling Pathways >>Neuronal Signaling >>AChE

References

[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163.

[2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777.

[3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	779.3±60.0 °C at 760 mmHg
Molecular Formula	C₃₆H₅₆O₁₁
Molecular Weight	664.82
Flash Point	237.0±26.4 °C
Exact Mass	664.382263
PSA	183.21000
LogP	5.47
Vapour Pressure	0.0±6.1 mmHg at 25°C
Index of Refraction	1.600
InChIKey	SFZVDNKTWPZIJG-ODXMFREGSA-N
SMILES	COC(=O)C1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CC(O)C(OC6OCC(O)C(O)C6O)C(C)(CO)C5CCC43C)C2C1

Safety Information

Hazard Codes	Xi

Synonyms

EsculentosideB

(2β,3β)-2,23-Dihydroxy-30-methoxy-30-oxo-3-(β-D-xylopyranosyloxy)olean-12-en-28-oic acid

Olean-12-ene-28,30-dioic acid, 2,23-dihydroxy-3-(β-D-xylopyranosyloxy)-, 30-methyl ester, (2β,3β)-

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