CAS 6926-14-3|8-O-Acetylharpagide
| Common Name | 8-O-Acetylharpagide | ||
|---|---|---|---|
| CAS Number | 6926-14-3 | Molecular Weight | 406.382 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 607.2±55.0 °C at 760 mmHg |
| Molecular Formula | C17H26O11 | Melting Point | 227-229℃ |
| MSDS | USA | Flash Point | 215.9±25.0 °C |
Names
| Name | 8-O-Acetylharpagide |
|---|---|
| Synonym | More Synonyms |
8-O-Acetylharpagide BiologicalActivity
| Description | 8-O-Acetylharpagide is an iridoid isolated from Ajuga reptans with antitumoral, antiviral, antibacterial, and anti-inflammatory activities. 8-O-Acetylharpagide also has a biological activity on isolated smooth muscle preparations from guinea pig[1][2]. |
|---|---|
| Related Catalog | Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Wen B, et al. Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens Thunb extract in rats. J Ethnopharmacol. 2013 May 20;147(2):503-8. [2]. Breschi MC, et al. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans. J Nat Prod. 1992 Aug;55(8):1145-8. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 607.2±55.0 °C at 760 mmHg |
| Melting Point | 227-229℃ |
| Molecular Formula | C17H26O11 |
| Molecular Weight | 406.382 |
| Flash Point | 215.9±25.0 °C |
| Exact Mass | 406.147522 |
| PSA | 175.37000 |
| LogP | -3.48 |
| Vapour Pressure | 0.0±3.9 mmHg at 25°C |
| Index of Refraction | 1.624 |
| InChIKey | CAFTUQNGDROXEZ-XBDCZORHSA-N |
| SMILES | CC(=O)OC1(C)CC(O)C2(O)C=COC(OC3OC(CO)C(O)C(O)C3O)C12 |
| Storage condition | ?20°C |
Safety Information
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles10
More Articles| [Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens extract in beagle dog]. Zhongguo Zhong Yao Za Zhi 38(12) , 2015-8, (2013) 8-O-acetylharpagide and harpagide are two kinds of effective component of Ajuga decumbens extract. A sensitive LC-MS/MS method has been established for pharmacokinetics of 8-O-acetylharpagide and harp... | |
| [Determination of acetylharpagide in Ajuga decumbens by HPLC]. Zhongguo Zhong Yao Za Zhi 31(4) , 289-90, (2006) To establish a method of the quantitative determination of acetylharpagide in Ajuga decumbens.The chromatographic conditions were as follows: a Phenomenex Luna C18 column was used, the mobile phase wa... | |
| [Studies on chemical constituents of Galeopsis bifida]. Zhongguo Zhong Yao Za Zhi 27(3) , 206-8, (2002) To investigate the chemical constituents of Galeopsis bifida.Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chem... |
Synonyms
| β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-7-(acetyloxy)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methylcyclopenta[c]pyran-1-yl |
| 6-Thio-8-propylthiotheophylline |
| (1S,4aS,5R,7S,7aS)-1-(β-D-Glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl acetate |
| 8-O-acetyl-harpagide |
| Harpagide 7-acetyl |
| Uric acid,1,3-dimethyl-8-propylthio-6-thio |
| 8-n-Propylthio-6-thiotheophyllin |
