CAS 108-86-1|Bromobenzene
Introduction：Basic information about CAS 108-86-1|Bromobenzene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromobenzene | ||
|---|---|---|---|
| CAS Number | 108-86-1 | Molecular Weight | 157.008 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 154.2±9.0 °C at 760 mmHg |
| Molecular Formula | C6H5Br | Melting Point | -31 °C |
| MSDS | ChineseUSA | Flash Point | 51.1±0.0 °C |
| Symbol | GHS02, GHS07, GHS09 | Signal Word | Warning |
Names
| Name | bromobenzene |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 154.2±9.0 °C at 760 mmHg |
| Melting Point | -31 °C |
| Molecular Formula | C6H5Br |
| Molecular Weight | 157.008 |
| Flash Point | 51.1±0.0 °C |
| Exact Mass | 155.957458 |
| LogP | 2.99 |
| Vapour density | 5.41 (vs air) |
| Vapour Pressure | 4.1±0.3 mmHg at 25°C |
| Index of Refraction | 1.556 |
| InChIKey | QARVLSVVCXYDNA-UHFFFAOYSA-N |
| SMILES | Brc1ccccc1 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Water Solubility | insoluble. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2699 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20411 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3882 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2700 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 gm/m3/2H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 817 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 2700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 14400 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3768 mg/kg/18D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 500 mg/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-HUNGARY:TWA 3 mg/m3;STEL 6 mg/m3;Skin JAN 1993 OEL-RUSSIA:STEL 3 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83863 No. of Facilities: 105 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 18936 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83863 No. of Facilities: 64 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1891 (estimated) No. of Female Employees: 238 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 500 mg/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-HUNGARY:TWA 3 mg/m3;STEL 6 mg/m3;Skin JAN 1993 OEL-RUSSIA:STEL 3 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83863 No. of Facilities: 105 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 18936 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83863 No. of Facilities: 64 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1891 (estimated) No. of Female Employees: 238 (estimated)
Safety Information
| Symbol | GHS02, GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226-H315-H411 |
| Precautionary Statements | P273 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R10;R38;R51/53 |
| Safety Phrases | S61-S45-S36/37 |
| RIDADR | UN 2514 3/PG 3 |
| WGK Germany | 2 |
| RTECS | CY9000000 |
| Packaging Group | III |
| Hazard Class | 3 |
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Synonyms
| phenyl bromide |
| phenyl benzyl thioether |
| BENZYL PHENYL SULFIDE |
| benzyl-phenylsulphide |
| Bromobenzene |
| Benzene, bromo- |
| BROMOBENZENE FOR SYNTHESIS |
| BROMOBENZENE (100 ML ) |
| Benzylthiobenzene |
| BROMBENZOL |
| EINECS 203-623-8 |
| Phenyl benzyl sulfide |
| Ph-S-CH2-Ph |
| Monobromobenzene |
| BROMO-BENZENE |
| 1-bromobenzene |
| MFCD00000055 |
