CAS 1414-45-5|Nisin

Introduction:Basic information about CAS 1414-45-5|Nisin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameNisin
CAS Number1414-45-5Molecular Weight3354.07000
Density/Boiling Point2967℃
Molecular FormulaC143H230N42O37S7Melting Point/
MSDSUSAFlash Point>110°(230°F)

Names

Namenisin
SynonymMore Synonyms

Nisin BiologicalActivity

DescriptionNisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species.
Related CatalogSignaling Pathways >>Anti-infection >>BacterialResearch Areas >>InfectionPeptides
In VitroNisin is classified as a Type A (I) lantibiotic that is synthesized from mRNA and the translated peptide contains several unusual amino acids due to post-translational modifications. Nisin is an antimicrobial peptide produced by certain Gram-positive bacteria that include Lactococcus and Streptococcus species[1].
References

[1]. Shin JM, et al. Biomedical applications of nisin. J Appl Microbiol. 2016 Jun;120(6):1449-65.

Chemical & Physical Properties

Boiling Point2967℃
Molecular FormulaC143H230N42O37S7
Molecular Weight3354.07000
Flash Point>110°(230°F)
Exact Mass3351.55000
PSA1390.67000
LogP3.42180
Storage condition2-8°C
Water SolubilitySoluble in water

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXn
Risk Phrases22-36/37/38
Safety Phrases22-24/25-36-26
RIDADRNONH for all modes of transport
WGK Germany3
RTECSQU3340000

Articles39

More Articles
Effect of lauric arginate, nisin Z, and a combination against several food-related bacteria.

Int. J. Food Microbiol. 188 , 135-46, (2014)

The effects of lauric arginate (LAE) and nisin Z, alone or in combination, on cell damage were investigated against Escherichia coli O157:H7, Listeria monocytogenes and Brochothrix thermosphacta, by s...

Piliation of Lactobacillus rhamnosus GG promotes adhesion, phagocytosis, and cytokine modulation in macrophages.

Appl. Environ. Microbiol. 81(6) , 2050-62, (2015)

Recently, spaCBA-encoded pili on the cell surface of Lactobacillus rhamnosus GG were identified to be key molecules for binding to human intestinal mucus and Caco-2 intestinal epithelial cells. Here, ...

Effect of combining nisin with modified atmosphere packaging on inhibition of Listeria monocytogenes in ready-to-eat turkey bologna.

Poult. Sci. 92(7) , 1930-5, (2013)

ABSTRACT The objective of this study was to evaluate the effect of nisin in combination with different types of packaging on the survival of Listeria monocytogenes in ready-to-eat low-fat turkey bolog...

Synonyms

EINECS 215-807-5
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