CAS 86917-57-9|(D-Pro4,D-Trp7·9·10)-Substance P (4-11)

Introduction:Basic information about CAS 86917-57-9|(D-Pro4,D-Trp7·9·10)-Substance P (4-11), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(D-Pro4,D-Trp7·9·10)-Substance P (4-11)
CAS Number86917-57-9Molecular Weight1207.40000
Density/Boiling Point/
Molecular FormulaC62H74N14O10SMelting Point/
MSDS/Flash Point/

Names

Name[D-Pro4,D-Trp7,9,10]-Substance P (4-11)
SynonymMore Synonyms

(D-Pro4,D-Trp7·9·10)-Substance P (4-11) BiologicalActivity

Description[D-Pro4,D-Trp7,9,10] Substance P (4-11) is a potent tachykinin antagonist[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Bailey SJ, et al. Effect of the tachykinin antagonist, [D-Pro4, D-Trp7,9,10] substance P-(4-11), on tachykinin- and histamine-induced inositol phosphate generation in intestinal smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1987 Mar;335(3):296-300.  

Chemical & Physical Properties

Molecular FormulaC62H74N14O10S
Molecular Weight1207.40000
Exact Mass1206.54000
PSA417.67000
LogP6.48210
InChIKeySFUBGXWEUDKBIR-XWYQIVALSA-N
SMILESCSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1)C(N)=O

Safety Information

WGK Germany3

Synonyms

(D-pro4,D-trp7,9,10)-substance P*fragment 4-11
Gpant-1,Ptt-SP (4-11)
Substance P,fragment 4-11,[D-Pro4,D-Trp7,9,10]
DPRO-GLN-GLN-DTRP-PHE-DTRP-DTRP-MET-NH2
(D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11)
D-Pro-L-Glu(NH2)-L-Glu(NH2)-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2
D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2
D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-MET-NH2
H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2
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