Introduction:Basic information about CAS 86917-57-9|(D-Pro4,D-Trp7·9·10)-Substance P (4-11), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (D-Pro4,D-Trp7·9·10)-Substance P (4-11) |
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| CAS Number | 86917-57-9 | Molecular Weight | 1207.40000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C62H74N14O10S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | [D-Pro4,D-Trp7,9,10]-Substance P (4-11) |
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| Synonym | More Synonyms |
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(D-Pro4,D-Trp7·9·10)-Substance P (4-11) BiologicalActivity
| Description | [D-Pro4,D-Trp7,9,10] Substance P (4-11) is a potent tachykinin antagonist[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Bailey SJ, et al. Effect of the tachykinin antagonist, [D-Pro4, D-Trp7,9,10] substance P-(4-11), on tachykinin- and histamine-induced inositol phosphate generation in intestinal smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1987 Mar;335(3):296-300. |
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Chemical & Physical Properties
| Molecular Formula | C62H74N14O10S |
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| Molecular Weight | 1207.40000 |
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| Exact Mass | 1206.54000 |
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| PSA | 417.67000 |
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| LogP | 6.48210 |
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| InChIKey | SFUBGXWEUDKBIR-XWYQIVALSA-N |
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| SMILES | CSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1)C(N)=O |
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Safety Information
Synonyms
| (D-pro4,D-trp7,9,10)-substance P*fragment 4-11 |
| Gpant-1,Ptt-SP (4-11) |
| Substance P,fragment 4-11,[D-Pro4,D-Trp7,9,10] |
| DPRO-GLN-GLN-DTRP-PHE-DTRP-DTRP-MET-NH2 |
| (D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11) |
| D-Pro-L-Glu(NH2)-L-Glu(NH2)-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2 |
| D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2 |
| D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-MET-NH2 |
| H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 |