CAS 190274-53-4|Calpain Inhibitor VI

Introduction：Basic information about CAS 190274-53-4|Calpain Inhibitor VI, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Calpain Inhibitor VI BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Calpain Inhibitor VI
CAS Number	190274-53-4	Molecular Weight	372.455
Density	1.2±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₁₇H₂₅FN₂O₄S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-yl)butanamide
Synonym	More Synonyms

Calpain Inhibitor VI BiologicalActivity

Description	Calpain Inhibitor VI (SJA6017) is a synthesized peptide aldehyde inhibitor of calpain. Calpain Inhibitor VI inhibits purified m-calpain with the IC50 of 80 nM. Calpain Inhibitor VI can be used for the research of cataract[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Proteasome
References	[1]. C Fukiage, et al. SJA6017, a newly synthesized peptide aldehyde inhibitor of calpain: amelioration of cataract in cultured rat lenses. Biochim Biophys Acta. 1997 Oct 24;1361(3):304-12.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Molecular Formula	C₁₇H₂₅FN₂O₄S
Molecular Weight	372.455
Exact Mass	372.151917
PSA	100.72000
LogP	3.21
Index of Refraction	1.512
InChIKey	WSJWUIDLGZAXID-HOCLYGCPSA-N
SMILES	CC(C)CC(C=O)NC(=O)C(NS(=O)(=O)c1ccc(F)cc1)C(C)C

Synonyms

N-[(4-Fluorophenyl)sulfonyl]-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-L-valinamide

N-((4-Fluorophenyl)sulfonyl)-L-valyl-L-leucinal

IN1503

Butanamide, 2-[[(4-fluorophenyl)sulfonyl]amino]-N-[(1S)-1-formyl-3-methylbutyl]-3-methyl-, (2S)-

(2R)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]butanamide

calpain inhibitor VI

4-fluorophenylsulfonyl-Val-Leu-CHO

(1'S,2S)-2-(4-fluorobenzenesulfonylamino)-N-(1-formyl-3-methylbutyl)-3-methylbutyramide

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