CAS 113274-57-0|Acetyl-Hirudin (55-65) (desulfated)
| Common Name | Acetyl-Hirudin (55-65) (desulfated) | ||
|---|---|---|---|
| CAS Number | 113274-57-0 | Molecular Weight | 1453.50000 |
| Density | / | Boiling Point | / |
| Molecular Formula | C66H92N12O25 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | Ac-Hirudin (55-65) (desulfated) |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Molecular Formula | C66H92N12O25 |
|---|---|
| Molecular Weight | 1453.50000 |
| Exact Mass | 1452.63000 |
| PSA | 598.43000 |
| LogP | 1.95970 |
| InChIKey | IEAUQSWIFZNYCL-UHFFFAOYSA-N |
| SMILES | CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(C)=O)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)O |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles4
More Articles| Lepirudin blunts endotoxin-induced coagulation activation. Blood 95 , 1729-1734, (2000) During sepsis, lipopolysaccharide (LPS) triggers the development of disseminated intravascular coagulation (DIC) via the tissue factor-dependent pathway of coagulation resulting in massive thrombin ge... | |
| Thrombin-dependent MMP-2 activity is regulated by heparan sulfate. J. Biol. Chem. 285 , 41270-41279, (2010) Like most metalloproteases, matrix metalloprotease 2 (MMP-2) is synthesized as a zymogen. MMP-2 propeptide plays a role in inhibition of catalytic activity through a cysteine-zinc ion pairing, disrupt... | |
| Chemical compensation in macromolecular bridge-binding to thrombin. Biochemistry 32 , 2947-2953, (1993) The binding energetics of eight synthetic peptides capable of interfering with thrombin function have been studied by steady-state measurements and clotting assays. The synthetic peptides are bifuncti... |
Synonyms
| ACETYL-HIRUDIN (55-65) (DESULFATED) |
| N-acetyl-hirudin fragment 55-65 |
| ACETYL-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN |
| AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN-OH |
| ac-hirudin fragment 55-65 non-sulfated |
| N-ACETYL-HIRUDIN AC-FRAGMENT 55-65 NON-SULFATED |
| AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN |
