Introduction：Basic information about CAS 106128-98-7|MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145),, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145), human,Ac-ASQKRPSQRHG |
|---|
| CAS Number | 106128-98-7 | Molecular Weight | 1293.39000 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C52H88N22O17 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145), human,Ac-ASQKRPSQRHG |
|---|
| Synonym | More Synonyms |
|---|
BiologicalActivity
| Description | Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)[1][2]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
|---|
| In Vitro | Myelin Basic Protein (1-11) (0-10 μg/mL) 刺激 MBP-TCR CD4 T 细胞产生 IL-2[1]。 |
|---|
| In Vivo | Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC 细胞 (i.p.) 在转移到受照射的 B10.PL 小鼠体内时会诱导实验性自身免疫性脑脊髓炎 (EAE)[1]。 Myelin Basic Protein (1-11) (100 μg，腹腔注射) 诱导成年小鼠对 MBP 的耐受性并预防 MBP 诱导的 EAE[2]。 |
|---|
| References | [1]. Dittel BN, et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9. [2]. Gaur A, et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4. |
|---|
Chemical & Physical Properties
| Molecular Formula | C52H88N22O17 |
|---|
| Molecular Weight | 1293.39000 |
|---|
| Exact Mass | 1292.67000 |
|---|
| PSA | 653.75000 |
|---|
| InChIKey | FFJQRTSMYDMULO-DAHMAOPXSA-N |
|---|
| SMILES | CC(=O)NC(C)C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CCCN=C(N)N)C(=O)NC(Cc1cnc[nH]1)C(=O)NCC(=O)O |
|---|
Synonyms
| myelin basic protein (135-145),human |
| ac-mbp (human,porcine,rat 1-11) |
| acetyl-mbp (135-145) (human) |
| mbp (1-11) human |
| acetyl-myelin a1 protein (135-145) (human) |
| acetyl-myelin basic protein (135-145) (human) |
| ac-asqkrpsqrhg |
| acetyl-golli-mbp1 hog7 (135-145) (human) |
| mbp (1-11),guinea pig,porcine,rabbit,rat |
| acetyl-myelin basic protein (human,rat,1-11) |
| Myelin Basic Protein (135-145) |
