Introduction：Basic information about CAS 957-77-7|5-Hydroxyuridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Hydroxyuridine |
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| CAS Number | 957-77-7 | Molecular Weight | 260.20 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C9H12N2O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-hydroxyuridine |
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| Synonym | More Synonyms |
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5-Hydroxyuridine BiologicalActivity
| Description | 5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Molecular Formula | C9H12N2O7 |
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| Molecular Weight | 260.20 |
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| Exact Mass | 260.064453 |
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| PSA | 145.01000 |
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| LogP | -1.51 |
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| Index of Refraction | 1.698 |
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| InChIKey | QXDXBKZJFLRLCM-UAKXSSHOSA-N |
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| SMILES | O=c1[nH]c(=O)n(C2OC(CO)C(O)C2O)cc1O |
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| Storage condition | 2-8°C |
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Synonyms
| 5-Hydroxy-uridin |
| 5-Hydroxy-uracil-ribotid |
| Uridine, 5-hydroxy- |
| Uridine,5-hydroxy |
| 5-hydroxy-uridine |
| 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-quinone |
| 5-Hydroxyuridine |
| 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione |
