CAS 50-66-8|6-(Methylthio)purine

[1]. Sugimura H, Takei H. Synthesis of 6-alkylpurine derivatives by nickel-complex-catalyzed coupling reaction of 6-(methylthio) purine derivatives with Grignard reagents. Bulletin of the Chemical Society of Japan, 1985, 58(2): 664-666.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UO8976000

CHEMICAL NAME :

Purine, 6-(methylthio)-

CAS REGISTRY NUMBER :

50-66-8

LAST UPDATED :

199709

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C6-H6-N4-S

MOLECULAR WEIGHT :

166.22

WISWESSER LINE NOTATION :

T56 BM DN FN HNJ IS1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Parenteral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

115 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,618,1982

TYPE OF TEST :

LD10 - Lethal Dose

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

94 mg/kg

TOXIC EFFECTS :

Gastrointestinal - other changes

REFERENCE :

PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 7,69,1970